Mental Illness-Depression Flashcards

1
Q

Definition of Mental Illness

A

clinically significant behavioral problems
associated with distress (painful symptoms)
causes disability (impairment in functioning)
A BIOLOGICAL ILLNESS THAT RESPONDS TO TREATMENT
Not to be confused with weakness of character

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2
Q

Facts about mental illness

A
leading cause of disability in the US
stigma and bias are persistent problems
its often chronic
patients have physical complaints
70% of the mentally ill are treated in primary care
TREATMENT IS NOT A CURE
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3
Q

Anti-Depressant medications

A

block the reuptake of norepinephrine, serotonic and some dopamine from the pre-synaptic neuron thereby increasing the amount of the neurotransmitter in the synapse

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4
Q

Mild Depression

A

counseling “talk therapy” may resolve the depressive episode.

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5
Q

Moderate to severe Depression

A

A combination of medication and counseling is the most effective approach.

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6
Q

Complete remission of symptoms

A

once a patient is in remission the antidepressant treatment should be continued for 6-12 months in order to promote complete recovery

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7
Q

33% of clients fail to fill their prescriptions

A

Those who do fill, less than 1/2 get a 2nd month of Tx. Less than 25% of clients who are prescribed meds take them for three months or longer.

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8
Q

SSRI-selective serotonin reuptake inhibitors
SNRI-seritonin norepineprine reuptake inhibitors
TCA- Tricyclic antidepressants
MOAI-Monoamine oxidase inhibitors

A

These are the classes of Anti-depressant medications

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9
Q

SSRI and SNRI-1st line treatment of major depressive disorder

A
Side effects:
GI upset (have client take at night)
sexual dysfunction
nervousness
HA
Less common SE are: weight gain, bleeding elevated BG, LFT and lipids
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10
Q

Sexual Dysfunction and antidepressants

A

Often a reason to discontinue
Wellbutrin (bupropion) is one drug that has the fewest sexual side effects and is a NDRI (Norepinephrine-dpamine reuptake inhibitor)

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11
Q

Wellbutrin-bupropion

A

Contraindicated if the patient has a seizure
disorder
Will not cause much weight gain
this drug has less sexualy dysfuntion

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12
Q

For prescribing antidepressants

A

Form an alliance with client
discuss concerns and those of family
Choose an SSRI, SNRI or NDRI

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13
Q

For a second episode of Depression

A

Continue therapy for two years after complete remission of symptoms

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14
Q

SNRI are good for those with psychomotor retardation

A

with depression

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15
Q

SSRI’s, SNRI’s

A

safest in overdose situations. Avoid TCA for this reason
Start low, go slow
For adolescents- recheck weekly for 4 weeks and then every other week for a month
When prescribing think about follow up. Only fill for that time.

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16
Q

Suicide ideation is usually in the 1st few months

A

SNRI for those who are tired feeling

17
Q

Tricyclics

A

2nd line for treating major depression
inexpensive
slow the gut so are good for IBS
Use caution if on SSRI as they can elevate levels

18
Q

TCS’s-side effects

A
Anticholergic-dry mouth, blurred vision, memory problems
Antiadrenergic-orthostatic hypotension
antihistaminergic-sedation and weight gain
cardiac dysrythmias
unsafe with cardiac disease
lethal in overdose
May be helpful in those who can't sleep
Especially not good for the elderly
19
Q

SSRI’s

A

It will take 2-3 weeks to see an initial effect and up to 6 weeks to achieve a full effect.

20
Q

Prozac
Zoloft
Paxil
Celexa

A

All come in generic form and are on the $4 list at wal-mat

Lexapro is newer and will be available in generic within the year.

21
Q

Atypical antidepressants

A
Wellbutrin
Triazolopyridine (Trazodone)-sedationg (helpful in those who can't sleep)
22
Q

Mao Inhibitors

A

No prescribed much in primary care
They interact
Special diet-No tyramine foods
Must avoid over the counter medications cold and allergy medications

23
Q

PMS and PMDD

A

treated with oral contraceptives or SSRI during the late luteal phase

24
Q

Significant changes in estrogen levels during postpartum

A

increase risk for depressive, psychotic or bipolar episode

25
paxil
Cannot be used in pregnancy
26
Sertraline-Zoloft
is one of the safest and most studied for treating depression during pregnancy and breastfeeding
27
Prozac-
Not recommended for breastfeeding mothers
28
Risks of antidepressant during pregnancy
Cardiac malformations (especially 1st trimester) newborn hypertension in 3rd trimester-SSRIS nenatal withdrawal syndrome low birth weight suicidal ideation for the first two weeks of therapy n those under 25 medical/legal risks
29
Anti-depressants during lactation-1st line
Zoloft and Pacil and Fluvox
30
General considerations for people
If tired-try Prozac- SNRI depression and anxiety-Paxil or lexapro Pain relief-maybe Cymbalta ar a TCA Cymbalta-maybe if they are in continenet or tx for diabetic neuropathy Remeron may be good for those who need to gain weight, agitated or have insomnia
31
Antidepressants in children
Only one safe for children under 8 is Fluoxetine (Prozac) At 12 others are approved. Remeber the black box warning. Once an adolescent is started, f/u in one week and then every 2 weeks then after a month based on symptoms
32
Anti-depressants in the elderly
SSRI and SNRI-drugs of choice. TCA's and MAOI's are contraindicated. Due to decreased renal clearance, reduced hepatic function start at one -third or one half of the adult dose.
33
Discontinuation Syndrome
``` Flu-like symptoms fatigue Myalgia decreased concentration, etc Happen with a med with short half life more often like Paxil. Prozac has longer half-life so not as likely ```
34
Serotonin syndrome
Could happen with combinations like SSRI & MAOIs Drug and herbal interactions SSRI's and St. Johns Wort
35
What is the worst that can happen
you activate a latent case of bi polar