menstruation and menopause pathosphsy Flashcards
1
Q
GnRH function
A
2
Q
GnRH increases what?
A
FSH
LH
3
Q
FSH function
A
causes the growth of follicles
4
Q
LH function
A
spikes in ovulation
5
Q
estrogen function
A
stimulates endometrial proliferation
6
Q
progesterone function
A
conditions the endometrium for implantation
7
Q
HCG function
A
stimulates the corpus luteum to produce progesterone until placenta develops
8
Q
what changes occur during menopause
A
9
Q
progestin MOA
A
induce endometrial secretory changes in estrogen-primed environment
10
Q
SERMs MOA
A
ER agonist in bone
ER antagonist in breast
11
Q
bisphosphonates MOA
A
fosamax and actonel- inhibit FPPS, preventing prenylation of proteins required for osteoclasts function
etidronate- incorporated into ATP analogs with osteoclasts, causing apoptosis
