Menstrual Disorders Flashcards

1
Q

what is the normal amount of blood lost during menstruation?

A
  • less than 80ml over 7 days (16 tsp)
  • average loss: 30-40ml (6-8tsp)
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2
Q

list the potential causes of heavy menstrual bleeding

A
  • uterine fibroids
  • endometrial polyps
  • endometriosis and adenomyosis
  • PID and infection
  • endometrial hyperplasia or carcinoma
  • PCOS
  • coagulation disorders
  • hypothyroidism
  • liver or renal disease
  • anticoagulant treatment
  • herbal supplements (gingseng, ginkgo, soya)
  • IUD
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3
Q

what are uterine fibroids?

A
  • non-cancerous growths made of muscle and fibrous tissue, also called myoma or lieomyoma
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4
Q

uterine fibroids symptoms

A
  • HMB
  • pelvic pain
  • urinary symptoms
  • pressure symptoms
  • backache
  • infertility
  • miscarriage
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5
Q

uterine fibroids diagnosis imaging

A

US

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6
Q

uterine fibroids levels of treatment

A
  • for HMB +/- small fibroids > COCP, POP, Mirena
  • large fibroids and fertility preservation desired > fibroid embolisation, myomectomy
  • submucosal fibroids > hysteroscopic fibroid resection
  • declined or failed medical treatment & fertility preservation not required > hysterectomy
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7
Q

endometriosis definition

A

Defined as endometrial tissue present outside the lining of uterus .During menstruation this ectopic tissue behaves the same as endometrium and bleeds

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8
Q

endometriosis symptoms

A
  • may present with HMB
  • painful menstrual cramps that worsen over time
  • pain during and after intercourse
  • lower back pain
  • painful bowel movements or urination
  • abnormal bleeding ot spotting between menstrual periods
  • infertility
  • fatigue
  • diarrhoea, nausea, bloating
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9
Q

what are the four stages of endometriosis?

A
  • stage 1, minimal: mall patches, surface lesions or inflammation on or around organs in pelvic cavity
  • stage 2, mild: more widespread and starting to infiltrate pelvic organs
  • stage 3, moderate: peritoneum or other structures, sometimes also scarring and adhesions
  • stage 4, severe: infiltrative and affecting many pelvic organs and ovaries, often with distortion of the anatomy and adhesions
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10
Q

endometriosis diagnostic investigations

A
  • pelvic exam
  • US, diagnostic laparoscopy
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11
Q

endometriosis management options

A
  • analgesia]
  • medical: COCP, POP, Mirena IUS, depot provera, GnRH analogues
  • ## surgical: ablation, hysterectomy endometrioma excision, pelvic clearance, hysterectomy
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12
Q

describe uterine adenomyosis

A
  • a condition where endometrium becomes embedded in myometrium
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13
Q

adenomyosis symptoms

A
  • HMB
  • may have dysmenorrhea
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14
Q

adenomyosis treatment

A
  • may respond to hormones partially
  • definitive treatment is hysterectomy
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15
Q

describe endometrial polyps

A
  • overgrowth of endometrial lining can lead to formation of pediculated structures called polyps which extend into endometrium
  • mostly benign
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16
Q

endometrial polyps diagnosis

A

US
hysteroscopy

17
Q

HMB investigations

A
  • thorough history
  • pelvic exam (speculum, bimanual) remember to look at cervix
  • clotting profile, thyroid function
  • pelvic US scan
  • laparoscopy if endometriosis suspected
  • endometrial biopsy from all patients aged 44 or above with HMB, refractory to medical treatment
18
Q

HMB medical treatment

A
  • tranexamic acid (antifibrolytics) reduces blood loss by 60%
  • mefenamic acid (prostaglandin inhibitor) reduces blood loss 30% and pain
  • hormonal contraception
  • COCP
  • LNG IUS and Depo-Provera reduces bleeding
  • oral progestogens e.g. provera
19
Q

hysterectomy risks

A
  • infection
  • dvt
  • bladder/bowel/vessel injury
  • altered bladder function
  • adhesions
20
Q

list some causes of oligo/amenorrhea

infrequent, absent or abnormally light menstruation

A
  • life changes: stress, eating disorders/malnourishment, obesity, intense exercise
  • hormones: POP, mirena, depot injection
  • primary ovarian insuffiecieny
  • PCOS
  • hyperprolactinaemia
  • prolactinomas
  • thyroid (Grave’s disease)
  • obstructions of the uterus, cervix, and/ or vagina
21
Q

PCOS is a metabolic syndrome, with diagnosis confirmed if 2 of the following 3 criteria are met:

A
  • abnormal US appearance of ovary
  • biochemical hyperandrogegism
  • clinical hyperandrogegism
22
Q

what is considered dysfunctional uterine bleeding?

A
  • DUB is a common disorder of excessive uterine bleeding affecting premenopausal women that is not due to pregnancy or any recognisable uterine or systemic diseases.