Menstrual Cycle Flashcards

1
Q

What are the 5 types of ovarian follicle?

A
Primordial follicle
Primary follicle
Pre-antral follicle
Early antral follicle
Mature / graafian follicle
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2
Q

What is the primordial follicle?

A

Primary oocyte surrounded by granulosa cells

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3
Q

What is the primordial follicle?

A

Primary oocyte surrounded by ZONA PELLUCIDA and granulosa cells

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4
Q

How does the primary follicle differ from pre-antral follicle?

A

Pre-antral follicle has a theca layer around the granulosa cells

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5
Q

What forms in the early antral follicle?

A

Antrum (fluid-filled space) in the granulosa cell layer

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6
Q

Which follicle, out of the developing antral follicles, is chosen for ovulation?

A

The dominant follicle

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7
Q

What day does ovulation occur?

A

Day 14

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8
Q

What does the corpus luteum release?

A

Progesterone
Oestrogen
Inhibin

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9
Q

If fertilisation doesn’t occur, how long does it take for the corpus luteum to reach maturation?

A

10 days

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10
Q

What triggers menstruation and the start of a new menstrual cycle?

A

The degeneration of the corpus luteum

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11
Q

What is the range of days for the menstrual cycle?

A

Every 21 - 35 days

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12
Q

Having sex during which period will most likely lead to fertilisation?

A

3 days before ovulation and 1 day after

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13
Q

Describe the stages of the follicular phase (7)

A
  1. GnRH stimulates release of FSH and LH from AP
  2. FSH causes follicle to mature
  3. Follicle secretes oestrogen in low amount
  4. LH is inhibited
  5. High oestrogen levels stimulate endometrial growth (proliferative phase)
  6. LH surge
  7. Ovulation
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14
Q

Describe the stages of the luteal phase (7)

A
  1. Follicle becomes corpus luteum
  2. CL releases inhibin, oestrogen and progesterone
  3. Inhibin (FSH), oestrogen and progesterone all inhibit HT and AP
  4. Progesterone maintains the endometrium (secretory phase)
  5. No fertilisation: corpus luteum degenerates
  6. Inhibition on HT and AP via I, O and P removed
  7. Menses
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15
Q

When is cervical mucus abundant, clear and watery and why? (3)

A

At the time of ovulation
Under the influence of oestrogen
Allows sperm to travel easily

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16
Q

When is cervical mucus thick and sticky and why?

A

After ovulation
Under the action of progesterone
Prevents bacteria from entering the uterus through the vagina

17
Q

How long are sperm viable after ejaculation?

A

4-6 days

18
Q

How long are eggs viable?

A

24-48 hrs after ovulation

19
Q

Secretion of what prevents antigenic rejection of the embryo?

A

Interleukin-2