Menstrual cycle Flashcards

1
Q

Day 1-4 = menstruation

A

Endometrium is shed as hormonal support withdrawn

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2
Q

Day 5-13 = proliferative phase

A
  • Pulses of GnRH from hypothalamus stimulate LH and FSH release = induce follicular growth
  • Follicles produce oestrodiol and inhibin = suppres FSH so 1 follicle and oocyte mature
  • Oestrodiol rises and +ve feedback on hypothalamus = LH rises = ovulation 36 hours after LH surge
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3
Q

Day 14-28 = luteal/secretory phase

A
  • follicle from which egg relased becomes corpus luteum
  • CL produces oestrodiol and prog = peak 1 week later
  • Secretory changes in endometrium = stromal cells enlarge, glands swell, blood supply increases
  • CL fails if egg not fertilised = prog and oest falls and menstruation follows
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