Menstrual Cycle Flashcards
Meiosis 1 gets arrested in
Diplotene stage of prophase
Primordial follicle
Primary oocyte + granulosa cells + theca cells
Initial recruitment of follicles is
Hormone independent
Maximum follicles are present at
5th month of IUL ( 6-7 million)
Functions of FSH
Prevents the follicles from undergoing atresia
Stimulates the follicles
FSH acts on
Granulosa cells
Granulosa cells secrete
Estrogen and inhibin B
Function of inhibin B
Negative feedback on FSH
Tumor marker for granulosa cell tumours
Inhibin B
Function of estrogen
-ive feedback on FSH
+ive feedback on LH
proliferation of endometrium
Effect of decrease in FSH d/t estrogen
All follicles die except one dominant follicle which has the max amount of FSH receptors
What happens when LH increases
LH surge
Acts on theca cells to produce androgens
Acts on granulosa cells by lutenizining them