Mens Health CE 2 Flashcards

1
Q

BPH mgmt drug classes
3

A

alpha-adrenergic antagonists
5-alpha-reductase inhibitors
pde-5 inhibitor

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2
Q

BPH mgmt - alpha receptors are

A

abundant in the prostate, base of bladder, prostate capsule and prostatic urethra

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3
Q

alpha-adrenergic antagonists MOA

A

decrease bladder outlet obstruction

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4
Q

decrease bladder outlet obstruction

A

alpha-adrenergic antagonists MOA

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5
Q

alpha-adrenergic antagonists - meds

A

terazosin/Hytrin
tamsulosin/Flomax
doxazosin/Cardura

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6
Q

alpha blockers - when to take

A

can cause hypotension, take at night; terazosin, doxazosin, tamsulosin

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7
Q

5 alpha reductase inhibitors MOA

A

reduce the size of the prostate; 6-12 months of treatment necessary to see benefit

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8
Q

reduce the size of the prostate; 6-12 months of treatment necessary to see benefit

A

5 alpha reductase inhibitors MOA

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9
Q

5 alpha reductase inhibitors meds
2

A

dutasteride/Avodart
finasteride/Proscar

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10
Q

PDE5 inhibitor
1

A

tadalafil/Cialis

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11
Q

tadalafil/Cialsis - takes how long to see effects for BPH

A

about a week

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12
Q

prostate cancer - how to screen

A

PSA

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13
Q

PSA - who and how often

A

those who have expected life of >10 years, q1-2 years if asymptomatic; stop about age 70-75

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14
Q

what percent of men dx with prostate cancer have an abnormal PSA

A

80%

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15
Q

PSA stands for

A

prostate specific antigen

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16
Q

PSA is a

A

protein produced by the prostate gland when it’s active

17
Q

PSA - bedrest

A

lowers

18
Q

PSA - exercise

A

no change

19
Q

PSA - DRE

A

increases but not clinically significant

20
Q

PSA - what can increase level
5

A
  1. ejaculation but resolves in 24 hours
  2. DRE but not clinical significant
  3. cycling
  4. prostate infection
  5. massage
21
Q

2nd most common cancer in men

A

prostate

22
Q

prostate cancer lifetime risk, dying risk

A

16%, 2.9%

23
Q

risk factor for prostate cancer
4

A
  1. older age
  2. African american
  3. family history of prostate cancer, especially before age 65
  4. known or likely BRCA1 or BRCA2 gene mutations
24
Q

normal PSA level

A

<4.0

25
Q

prostate cancer assessment findings
4

A
  1. most are asymptomatic when dx
  2. asymmetry, induration, nodularity suspicious of prostate cancer even if normal PSA
  3. prostate feels hard, and/or nodular
  4. new onset ED
26
Q

can UTI cause increase in PSA

A

not likely

27
Q

how to dx hernia

A

physical exam, if not then US

28
Q

how if asymptomatic hernia managed

A

referral

29
Q

painless swelling of one testicle

A

testicular cancer