Menopause

Question 1

Average age of menopause?

Answer 1

52

Question 2

3 important oestrogens?

Answer 2

oestrodiol, oestrone and oestriol

Question 3

oestrogen produced by ovaries?

Answer 3

oestrodiol

Question 4

oestrogen produced by peripheral conversion of androgens in adipose tissue?

Answer 4

oestrone

Question 5

Which is E1 and E2, and which is more biologically active?

Answer 5

oestrodiol = E2
oestrone = E1
E2 is more biologically active

Question 6

Vasomotor symptoms?

Answer 6

Hot flushes

Nights sweats

Question 7

General other symptoms?

Answer 7

Headache
Fatigue
Insomnia
Arthralgia
Dizziness

Question 8

Psychological symptoms?

Answer 8

Poor memory
Loss concentration
Irritability
Low mood
Anxiety

Question 9

What type of HRT is Only to be used in women who have had a total hysterectomy?

Answer 9

oestrogen only

Question 10

What is Sequential Combined HRT?

Answer 10

Oestrogen for 28 days

Progestogen for 10-14 days

Question 11

What is combined continuous HRT?

Answer 11

Oestrogen combined with progestogen for 28 days

Question 12

When should combined continuous HRT be used?

Answer 12

This should not be started until 1 year after the LMP or aged 54
Should also be used after 2 years of sequential therapy if under the age of 54

Question 13

What is tibolone an alternative to?

Answer 13

CC HRT

Question 14

What is tibolone?

Answer 14

Synthetic steroid

Question 15

What type of fractures does tibolone not reduce?

Answer 15

hip