Menopause Flashcards
menopause defined
one year of no mentstraul bleeding
average age of menopause
51
labs you draw for menopause
FSH, LH and estrodiol
lab findings for menopause
FSH great than 30 and no menses for a yeat
_________ is associated with early menopause
moking
estrodiol less than ________ for dx
20
fertility is still present in __________
perimenoupause, when you have light er bleeding, spotting, irregularity
as many as _______% of women get hot flashes
75
tx for vasomotor sx
estrogens, progestins, clinidine, SSRI, black cohosh, gabapentin
treat vag sx early, because on ce lost, you cant get it back, but it will abate, so If you treat it you can _______ over time
taper
premarin, equein estrogen
systemic HRT
the point of tx is to treat as small as needed location, with the _________ possible dose to improve safety profiles
lowest
decreased _________ may contribute to a decline in sexual desire. treatment for this is off label
testerone
vaginal atrophy increases the risk for ____________
STI/HIV
midlife women may have memory and concentrations problems…. this is due to normal aging and or mood. studies show that ________- can increase this decline
estrogen/progestin
predicit factor at midlife is ________
prior hx of MDD
skin and hair changes
hair loss, skin become thinnger and less elastic, nails become birttle, hirutism
peak bone mass is (age)
25-30
women can loose up to ________ of bone mass in 5-7 years after menopause
5-7
t scores
t store -1–2.5 osteopenic
less than -2.5 osteoporoctic
what should we supplement with _______ at 30yo to maintain good bone health
calcium and vitamin D
before menopause, very few women die from ______
CHD
after menopause CHD increases; there are estrogen and progesterone receptors present in heart and aorita
2-3x
breast cancer is a _________ distribution
bimodal (30yo, agressive and fiast) and 70’s (slow growing and treatable usually…doesn’t kill them)
screen for these cancers for these women
breast, colorectal, cervical
approved inidcations for HRT
prevention of oestoporosis, tx of vasomotor sx, tx of vag atrphoy
ET is unapposed rxed for women who do/do not have unteurs
do not have a utures
ET is also used locally in low doses for any woman with _________ and has a utures
vag sx
EPT, estrogen progestroen therapy protects from _________ which can actually be caused by ____________
endometrial, estrogen alone
Absolute risks for HT:
thrombosis, stroke, and CVD (MI)
PERSONAL MI? They are NOT a canidate for ________AT ALL
HRT
The older you are when initatieng HRT, the worse the ______
risks
BHT: bioidentical hormone therapy. Some are FDA approved, some are unapproced and untested from compounding pharmacys
other contradictions for HRT (oral)
undxed vag bleeding, DVT or PE, MI/Stroke, liver disease, history of endometrial or breast cancer (+/- with fam hx)
________ is FDA approved for menoupausal sx
paroxetien
vasomotor sx can be treated with really well with ________
gabapentin, especially to help with sleep too (sedating)
clonidine is great because it comes in _________ form
pathc