Meningitis Flashcards
meningococcal infection is spectrum of diseases caused by
the bacterium neisseria meningitides
meningococcal infection
meningitis, septicemia or a combination of both
neisseria meningitides Gram –ve or Gram +ve
Gram –ve
neisseria meningitides motile or non motile
non motile
neisseria meningitides non spore forming or spore forming
non spore forming
cocci are arranged in pairs with their flatted surface faces each other
neisseria meningitides
how many serogroups are there of neisseria meningitides
13
mainly implications of meningococcal meningitis
A,B,C ,Y & W135
serotype most prevalent in europe and north america
serotype b
type A & occasionally sero -group C & recently W135
Africa & Asia
in europe and north america peak incidence is during which seasons
winter & spring
in africa peak incidence is during which season
dry season
in 2000 an epidemic of which sero - group associated with hajji in KSA
W135
four types of meningitis
- meningoccocal meningitis (moderate type)
- fulminate type (shock type , meningoencephalitis)
- mixed type (menigicoccoemia-meningitis)
- mild acute (mild acute meningiococoemia)
clinical manifestations during meningitic period
kernig brudziski
No vaccine effective against which serogroup
group B
most effective drug
penicillin g
other used drugs in treatment
ampicillin and chloramphenicol and third generation cephalosporin’s
specific treatment is given to nasopharyngeal carries
minocycline & rifampicin
previously used treatment
sulphadiazine
drug associated with vestibular reaction
minocycline
which sero-group vaccine isn’t recommended for children under 2
Sero-group C
only serotype that does not contraindicate in pregnant women
Sero-group A
is effective in age after one year and above
Conjugated sero – group A
given to those exposed to outbreak if its too late for vaccine
chemoprophylaxis
Intimate contacts what should be considered as a preventative measure
prophylaxis
vaccine preventable sero - group
A , C
