Meningitis Flashcards
1
Q
Which pathogen cause meningitis the most
A
- Strep pneumo
- N. meningitidis
- H. flu
- Listeria
2
Q
Listeria is most likely to effect what groups
A
- Old
- Neonates
- Alcoholics
3
Q
N. meningitidis is most common in what group
A
-College age teens
4
Q
Clinical presentation
A
- Headache
- Fever
- Stiff neck
- Photophobia
5
Q
Cerebrospinal Fluid changes in meningitis
A
- Increased WBC count
- Increased neutrophils
- Increased protein levels
- Decreased glucose levels
6
Q
Diagnostics of Meningitis
A
CSF evaluation
-Gram stain and culture
7
Q
Goals of Therapy
A
- Eradicate infection
- Decrease signs and symptoms of infection
- Prevent complications
8
Q
Management of Meningitis
A
- Empiric abx
- Antiinflammatories
- Fluids
- Electrolytes
- Antipyretics
- Analgesics
9
Q
Characteristics that improve abx penetration
A
- Low molecular weight
- Non ionized
- Low protein binding
- Lipophilic
10
Q
Empiric therapy rules
A
- Initiate with in 30mins of presentation
- Continue for 48 to 72hrs or until diagnosis of meningitis can be ruled out
- Once pathogen is identified, narrow therapy
11
Q
Empiric Meningitis Therapy
A
-Ceftriaxone
plus
-Vancomycin
12
Q
Empiric Regimens in elderly, neonates, and alcoholics
A
- Have an increased risk of listeria
- Add ampicillin to the Vanco and Ceftriaxone
13
Q
When to add Dexamethasone
A
Only for
- Strep pneumo
- H. flu
14
Q
Treatment of N. meningitidis meningitis
A
- Ceftriaxone 2g IV q4-6h
- Drop Vanco, amp, dexamethasone
- Duration 7 days
15
Q
When to do Prophylaxis for meningitis
A
- At least 4hrs of contact with infected
- Making out
- Resuscitation
