Meningeal coverings Flashcards

1
Q

What are the three meningeal coverings of the brain?

A

Dura, arachnoid, and pia matter. Arachnoid+pia=leptomeninges

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2
Q

What are the two dural layers in the brain?

A

Two dural layers in brain, one in spinal cord. Outer periostal layer: attached to skull, contains meningeal arteries. Inner meningeal layer: close to arachnoid, continuous with spinal dura.

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3
Q

Where are epi/extradural spaces in brain and spine?

A

No epidural space in cranium because dura is fused with skull. This is a potential space that becomes filled only in pathological conditions (e.g. epidural hematoma). In spinal cord, spinal extradural space contains vertebral plexus.

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4
Q

Describe sensory function of dura.

A

Dura is pain sensitive (headaches, stretching dura) - trigeminal and cranial nerves.

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5
Q

What are the four dural folds?

A
  1. Falx cerebri: separates left and right hemispheres
  2. Falx cerebelli: separates left and right cerebellum
  3. Tentorium cerebelli: on top of cerebellum, horizontal
  4. Diaphragma sellae: roof of sellae turcica, covers pituitary, horizontal
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6
Q

What are the 13 sinuses?

A

superior sagital, inferior sagital, straight, occipital, confluence of sinuses, transverse (R and L), sigmoid (R and L), cavernous, intercavernous, sphenoparietal, superior petrosal, inferior petrosal, basilar.

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7
Q

What are emissary veins?

A

Connect extracranial veins to venous sinuses inside the cranium. Important route for spread of infection.

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8
Q

Describe arachnoid

A

Subarachnoid space (between arachnoid and pia) contains CSF. Arachnoid trabeculae attaches to pia and suspends brain.

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9
Q

Describe function of arachnonid granulations/villi

A

Absorb most of the CSF and deliver it to the dural venous sinuses. Malfunction of archnoid granulation -> hydrocephalus.

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10
Q

Where does pia end? Dura/arachnoid?

A

Pia ends as filum terminale at L1/L2. Dura and arachnoid at S2.

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11
Q

What does a tear in meningeal artery lead to?

A

Epidural bleeding (between skull and outer periostal layer, pushing dura into head)

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12
Q

What does a rupture of cerebral artery lead to?

A

Subarachnoid bleeding

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13
Q

What does tearing cerebral vein as it penetrates arachnoid on way into venous sinus lead to?

A

Subdural bleeding (between inner meningeal layer and arachnoid).

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14
Q

Name the ventricles and areas of the brain they are associated with

A

Lateral in telencephalong (one for each hemisphere). Midline third ventricle (diencephalon). Midline fourth ventricle (rhombencephalon).

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15
Q

Describe flow of CSF through ventricles.

A

Lateral ventricle -> interventricular foramen of monro -> 3rd ventricle -> aqueduct of silvius -> 4th ventricle -> foramen of magendie (medial) and foramen of Luschka (2 lateral)

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16
Q

How is fourth ventricle connected to CSF circulation?

A

1 median foramen of Magendie. 2 lateral foramen of Luschka.

17
Q

Describe function and location of choroid plexus

A

Makes CSF (secreted by choroid epithelium). Found in the roof of 3rd and 4th ventricles and medial walls of lateral ventricles. Rate of formation = 500mL/day. Total V=90-150mL, ~23mL in ventricles, rest in subarachnoid space.

18
Q

Name an important large pocket of subarachnoid space

A

Cisterna magna: between medulla and inferior surface of cerebellum

19
Q

Describe function of CSF

A

Mechanical support, cushioning - dampens effects of trauma. Helps remove metabolites from CNS and is route for spread of “neuroactive” hormones.

20
Q

Distinguish between communicating and non-communicating hydrocephalus.

A

Hydrocephalus occurs when CSF circulation is blocked or its absorption is impeded.
Communicating: ventricles can still communicatie, i.e. no blockage in ventricle system.
Non-communicating: ventricles cannot communicate, i.e. blockage in ventricle system.

21
Q

Describe circumventricular organs and give a sensory and secretory example

A

Around 3rd and 4th ventricles and lack a BBB.
Sensory=area postrema
Secretory=neurohypophysis