Mendelian inheritance

Question 1

what are the features of autosomal dominant inheritance

Answer 1

-each child has 50% chance of inheriting the mutation
-no skipped generations
-male to male transmission occurs here
-male and female transmit

Question 2

what are examples of autosomal dominant disorder

Answer 2

Achondroplasia
huntingsons dieases

Question 3

what is x-linked inheritance/features of it

Answer 3

-no male to male transmission
-can skip generations
-only males are affected
-unaffected women can transmit the condition aswell as affected man

Question 4

in x-linked inheritance who can transmit the condtion

Answer 4

affected males AND UNAFFECTED females

Question 5

example of x-linked inheritance

Answer 5

duchenne muscular dystrophy
hunter syndrome

Question 6

what is duchenne msucalr dystrophy characteristed by?

Answer 6

weakness and progessive muscle degradation

Question 7

how is achondroplasia inherited ?

Answer 7

by autosomal dominant

Question 8

give 3 examples of autosomal recessive inheritance

Answer 8

cystic fibrosis , sickle cell anemia and TAY..

Question 9

what causes mendelian disease to occur

Answer 9

multiple genes in the same molecular pathway

Question 10

how many genes do you need for autosomal recessive inheritance

Answer 10

2 diseased genes, 1 acts as a carrier

Question 11

how many genes do u need for autosomal dominant

Answer 11

only need 1 diseases gene

Question 12

describe what achondroplasia actually is as a disease

Answer 12

genetic condition that affects a protein in the body called the fibroblast growth factor receptor

Question 13

outcome when the father has the haemophilia gene and the mother is unaffected

Answer 13

all their daughters will carry the haemophilia gene but their sons will be unaffected

Question 14

outcome when the mother has the haemophilia gene but the father is unaffcted

Answer 14

daughter and son have 50 percent change of carrying the gene