Mendel Inher

Question 1

Autosomal recessive carrier

Answer 1

Has one functional protein and one nonfunctional or missing protein

Question 2

Autosomal recessive affected

Answer 2

• 2 reduced function proteins

Question 3

Sickle cell and cystic fibrosis odds if both parents are carriers

Answer 3

• 1/4 chance of affected/not affected

- 1/2 chance carrier

Question 4

Cystic fibrosis population risk

Answer 4

1/25

Question 5

Autosomal recessive odds if one parent is a carrier

Answer 5

• 1/2 chance carrier

- 1/2 chance non-carrier

Question 6

Autosomal dominant

Answer 6

• No skipping generations
• Equal between males and females
• Huntington’s and achondroplasia

Question 7

Autosomal dominant chances if one parent is affected

Answer 7

1/2 chance of affected

1/2 chance of unaffected

Question 8

X-linked inheritance

Answer 8

• Classically only males affected
• Can skip generations
• Unaffected women and affected men can transmit condition
• Haemophilia and Duchenne’s muscular dystrophy

Question 9

X-linked. If father is affected and mother is not

Answer 9

• As it is X linked, boys will not get

- Girls will be carriers

Question 10

X-linked. If mother is carrier and father is unaffected

Answer 10

• 50% chance boys will have haemophilia, depends on which X they get from their mum
• 50% chance girls will carry gene