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Renal > Membranous glomerulonephritis > Flashcards

Membranous glomerulonephritis Flashcards

1
Q

Renal biopsy demonstrates:

[…] microscopy: the […] […] is thickened with […] electron dense deposits. This creates a ‘[…] and […]’ appearance

A

Renal biopsy demonstrates:

electron microscopy: the basement membrane is thickened with subepithelial electron dense deposits. This creates a ‘spike and dome’ appearance

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2
Q

Causes

idiopathic: due to anti-phospholipase A2 antibodies ([…])
[…] (in 5-20%): prostate, lung, lymphoma, leukaemia
Others

A

Causes

idiopathic: due to anti-phospholipase A2 antibodies
infections: hepatitis B, malaria, syphilis
malignancy (in 5-20%): prostate, lung, lymphoma, leukaemia
drugs: gold, penicillamine, NSAIDs
autoimmune diseases: systemic lupus erythematosus (class V disease), thyroiditis, rheumatoid

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3
Q

Mem glomer mx

A

ACEi or ARB

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Renal (4 decks)

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