Acute interstitial nephritis

Question 1

[…]% of drug-induced acute kidney injury.

Answer 1

25% of drug-induced acute kidney injury.

Question 2

Causes of acute interstitial nephritis

drugs: the most common cause, particularly […]
[…]
rifampicin
[…]
allopurinol
furosemide
systemic disease: […], sarcoidosis, and Sjögren’s syndrome
infection: […] virus , staphylococci

Answer 2

Causes of acute interstitial nephritis

drugs: the most common cause, particularly antibiotics
penicillin
rifampicin
NSAIDs
allopurinol
furosemide
systemic disease: SLE, sarcoidosis, and Sjögren’s syndrome
infection: Hanta virus , staphylococci

Question 3

histology: marked […] […] and interstitial […] in the […] tissue between renal […]

Answer 3

histology: marked interstitial oedema and interstitial infiltrate in the connective tissue between renal tubules

Question 4

Key feature

Answer 4

fever, rash, arthralgia
eosinophilia

Question 5

Investigations in AIN
sterile […]
white […] […]

Answer 5

Investigations
sterile pyuria
white cell casts