membranes - williamson Flashcards
1
Q
phospholipid structure?
A
cis
O link tails
- makes membranes thinner and fluid
2
Q
sphingolipid structure?
A
NH links tails
trans
makes mems more ordered - gel
3
Q
cholesterol structure?
A
short and fat
makes membrane thicker - planar
4
Q
4 methods membrane curvature fixation?
A
scaffolding
amphipathic helix insertion
cytoskeleton
mem proteins - oligomerisation/shape
5
Q
state lipid distribution of the IM and OM and between 2 leaflets
A
want a gel outer membrane (chol+sphingo) fluid inner mems (little sphingo) Inner leaflet: PI Outer leaflet: Sphingo flippase flips lipids
6
Q
protein types on leaflets?
A
outside: GPI
inside: lipid anchored
7
Q
which lipids/proteins are present in membrane rafts?
A
thicker lipids - chol/sphingo
proteins: GPI/palmitoyl
