membranes

Question 1

flipase

Answer 1

p-type

PE and PS inside

Question 2

flopase

Answer 2

moves outside

Question 3

scramblease

Answer 3

moves towards equilibrium

Question 4

membrane sections of proteins are never disordered because

Answer 4

lipid tails are unable to hydrogen bond with the protein backbone or side chains

Question 5

GLUT1

Answer 5

RBCs high affinity

Question 6

GLUT2

Answer 6

general organs

low affinity

Question 7

GLUT3

Answer 7

Brain

high affinity

Question 8

GLUT4

Answer 8

adipose and muscle
insulin dependent
(signals it to the cell surface)

Question 9

GLUT5

Answer 9

intestine (uses 5 in 2 out and SGLT-1 for NA glu in)

FRUCTOSE

Question 10

symporter

Answer 10

2 in same direction

Question 11

antiporter

Answer 11

2 in opposite directions

Question 12

P-type

Answer 12

plasma membrane, must be phosphorylated

Question 13

F-Type

Answer 13

mitochondria H+ pump

Fi and Fo

Question 14

V-Type

Answer 14

Vesicle and same as F-Tpye

Question 15

ABC

Answer 15

Multi-Drug resistance

ATP Binding Cassette

Question 16

SERCA Pump

Answer 16

P-Type
Ca2+ pump
2 per ATP
normal level :SR 500 IC 0.1 EC 1500

Question 17

NaK Pump

Answer 17

P-Type

3Na out 2 K in per ATP

Question 18

aquaporin

Answer 18

channel

rotates H2O causing specificity and blocking H+

Question 19

which of the following do NOT significantly affect membrane fluidity

Answer 19

ratio of glycophospholipid to sphingoipid

Question 20

GLUT1, the most common glucose transporter, would be considered a

Answer 20

uniporter

Question 21

The K channel discriminates between K and Na by

Answer 21

the carbonyls of the protein backbone replace the hydration sphere of K very precisely

Question 22

Voltage sensor on channels?

Answer 22

Helicies

Question 23

Cystic fibrosis - Main defect

Answer 23

CFTR Chloride transporter

Question 24

Cystic fibrosis - Test

Answer 24

Sweat Test

Question 25

Cystic fibrosis - exact defect

Answer 25

PHE 508 deletion

Question 26

Cystic fibrosis - class hierarchy

Answer 26

I to VI

worst to least

Question 27

Cystic fibrosis - most common

Answer 27

II mis-folded protein

50% functionality is ok