Glycolysis - From Internet Flashcards

1
Q

(Step 1) Glucose _ Glucose-6-P is catalysed by

A

Hexokinase

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2
Q

(Step 1) Glucose and ATP _ ADP + Pi leads to

A

Glucose-6-P

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3
Q

(Step 1) Hexokinase is regulated by

A

Glucose-6-P

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4
Q

(Step 2) Glucose-6-P _ Fructose-6-P is catalysed by

A

Phosphoglucoisomerase

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5
Q

(Step 2) Glucose-6-P through isomerisation leads to

A

Fructose-6-P

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6
Q

(Step 3) Fructose-6-P _ Fructose-1,6-BP is catalysed by

A

Phosphofructokinase

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7
Q

(Step 3) Fructose-6-P and ATP _ ADP + H_ leads to

A

Fructose-1,6-BP

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8
Q

(Step 3) Phosphofructokinase is activated by

A

Fructose-2,6-BP and AMP

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9
Q

(Step 3) Phosphofructokinase is inhibited by

A

ATP, H_ and citrate

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10
Q

(Step 4) Fructose-1,6-BP _ Glyceraldehyde-3-P and Dihydroxyacetone phosphate is catalysed by

A

Aldolase

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11
Q

(Step 4) Fructose-1,6-BP is cleaved to produce

A

Glyceraldehyde-3-P and Dihydroxyacetone phosphate

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12
Q

(Step 5) Glyceraldehyde-3-P + Dihydroxyacetone phosphate _ 2 Glyceraldehyde-3-P is catalysed by

A

Triose-phosphate isomerase

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13
Q

(Step 5) Glyceraldehyde-3-P + Dihydroxyacetone phosphate are isomerised to

A

2 x Glyceraldehyde-3-P

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14
Q

(Step 6) 2 x Glyceraldehyde-3-P _ 2 x 1,3-Bisphosphoglycerate is catalysed by

A

Glyceraldehyde-3-P dehydrogenase

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15
Q

(Step 6) 2 x Glyceraldehyde-3-P and NAD_ + Pi leads to the energy rich

A

2 x 1,3-Bisphosphoglycerate

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16
Q

(Step 7) 2 x 1,3-Bisphosphoglycerate _ 2 x 3-Phosphoglycerate is catalysed by

A

Phosphoglycerate kinase

17
Q

(Step 7) 2 x 1,3-Bisphosphoglycerate and 2 x ADP + H_ (substrate level phosphorylation) leads to

A

2 x 3-Phosphoglycerate

18
Q

(Step 8) 2 x 3-Phosphoglycerate _ 2 x 2-Phosphoglycerate is catalysed by

A

Phosphoglyceromutase

19
Q

(Step 8) 2 x 3-Phosphoglycerate is isomerised to

A

2 x 2-Phosphoglycerate

20
Q

(Step 9) 2 x 2-Phosphoglycerate _ 2 x Phosphoenolpyruvate is catalysed by

A

Enolase

21
Q

(Step 9) 2 x 2-Phosphoglycerate is turned into the energy rich compound

A

2 x Phosphoenolpyruvate

22
Q

(Step 10) 2 x Phosphoenolpyruvate _ 2 x Pyruvate is catalysed by

A

Pyruvate kinase

23
Q

(Step 10) 2 x Phosphoenolpyruvate and 2 x ADP + H_ _ 2 x ATP (substrate level phosphorylation) leads to

A

2 x Pyruvate

24
Q

(Step 10) Pyruvate kinase is activated by

A

Fructose-1,6-BP

25
Q

(Step 10) Pyruvate kinase is inhibited by

A

ATP and alanine

26
Q

Net ATP yield

A

2

27
Q

Net NADH yield

A

2

28
Q

Takes place in

A

cytosol