Glycolysis - From Internet Flashcards
(Step 1) Glucose _ Glucose-6-P is catalysed by
Hexokinase
(Step 1) Glucose and ATP _ ADP + Pi leads to
Glucose-6-P
(Step 1) Hexokinase is regulated by
Glucose-6-P
(Step 2) Glucose-6-P _ Fructose-6-P is catalysed by
Phosphoglucoisomerase
(Step 2) Glucose-6-P through isomerisation leads to
Fructose-6-P
(Step 3) Fructose-6-P _ Fructose-1,6-BP is catalysed by
Phosphofructokinase
(Step 3) Fructose-6-P and ATP _ ADP + H_ leads to
Fructose-1,6-BP
(Step 3) Phosphofructokinase is activated by
Fructose-2,6-BP and AMP
(Step 3) Phosphofructokinase is inhibited by
ATP, H_ and citrate
(Step 4) Fructose-1,6-BP _ Glyceraldehyde-3-P and Dihydroxyacetone phosphate is catalysed by
Aldolase
(Step 4) Fructose-1,6-BP is cleaved to produce
Glyceraldehyde-3-P and Dihydroxyacetone phosphate
(Step 5) Glyceraldehyde-3-P + Dihydroxyacetone phosphate _ 2 Glyceraldehyde-3-P is catalysed by
Triose-phosphate isomerase
(Step 5) Glyceraldehyde-3-P + Dihydroxyacetone phosphate are isomerised to
2 x Glyceraldehyde-3-P
(Step 6) 2 x Glyceraldehyde-3-P _ 2 x 1,3-Bisphosphoglycerate is catalysed by
Glyceraldehyde-3-P dehydrogenase
(Step 6) 2 x Glyceraldehyde-3-P and NAD_ + Pi leads to the energy rich
2 x 1,3-Bisphosphoglycerate