Membranes Flashcards
plasma membrane
outer boundary of cell that separates from the world
phosphoglycerides
diacylglycerides with small functional head groups linked to the glycerol backbone by phosphate ester bonds
sphingolipids
ceramides formed by the attachment of sphingosine to fatty acids
glycolipids
receptors for extracellular ligands
what kinds of lipids are on the cytosolic leaflet of pm?
phosphatidylserine
phosphatidylethanolamine
phosphatidylinositol
what kind of lipids are on the exoplasmic leaflet of pm?
sphingomyelin
phosphatidylcholine
cholesterol
smaller and less amphipathic lipid that is only found in animals
N-glycosidic linkage
attached to asp
O-glycosidic linkage
attached to ser or thr
passive transport
does not require energy
active transport
requires energy
facilitated diffusion
diffusion facilitated by a protein transporter
how can molecules passively diffuse through membranes?
must move from high concentration to low concentration
substance can dissolve in lipid bilayer or pass through pore
hypotonic
net water gain; cell swells
hypertonic
net water loss; cell shrinks
isotonic
no net loss or gain of water
aquaporins
specialized channels for H2O transport
voltage-gated channels
open vs. closed based on differences in ionic charge between the inside and outside of cell
ligand-gated channels
open vs. closed based on a ligand binding to the channel (conformational change)
opening/closing of eukaryotic K+ channel
once opened more than 10 million K+ ions can pass through per second
after open for a few milliseconds, movement of ions is stopped (inactivation)
functions of cyctic fibrosis
Cl- channel; transportes bicarb ions; blocks Na+ channels
facilitative transporters
transmembrane proteins that bind a substance and transport it across the membrane
which direction do facilitative transporters transport molecules in?
either direction
sodium potassium pump moves ____ inside and ____ outside
potassium; sodium