Membranes Flashcards

1
Q

Which is polar, the hydrophilic head or hydrophobic tail?

A

hydrophilic head

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2
Q

Which is negatively charged, the hydrophilic head or hydrophobic tail?

A

hydrophilic head

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3
Q

What is the charge of the hydrophobic tail?

A

No charge

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4
Q

What does cholesterol contribute to?

A

the fluidity and stability of the membrane.

stiffens membrane

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5
Q

Do peripheral proteins penetrate the membrane?

A

No

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6
Q

What do the Glycoproteins and glycolipids together form?

A

glycocalyx

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7
Q

Describe the 3 important functions of the lipid bilayer.

A

It forms the basic structure of the membrane.
Its hydrophobic interior serves as a barrier
The cell can maintain differences in solute composition and concentrations inside/outside the cell
It is responsible for the fluidity of the membrane
Enables the cell to change shape (e.g. RBC or a muscle cell)

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8
Q

What type of proteins form water-filled highly-selective ion channels?

A

transmembrane

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9
Q

What is an example of a disease where there are genetic mutations in channels?

A

cystic fibrosis

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10
Q

What carrier is expressed by thyroid gland cells?

A

iodine

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11
Q

Where are docking marker receptors located and what do they do?

A

Located on the inner membrane surface

Interact with secretory vesicles leading to exocytosis of the vesicle contents

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12
Q

What is an example of a membrane bound enzyme which can be located on either membrane surface?

A

protein kinase C

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13
Q

What are caherins and integrins?

A

Cell adhesion molecules

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14
Q

What do cadherins do?

A

helps hold cells within tissues together

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15
Q

What do integrins do?

A

span the plasma membrane acting as a link between extra- and intra-cellular environments

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16
Q

What serve as self-identify markers that enable cells to identify and interact with one another?

A

membrane carbohydrate

17
Q

What are different cell markers important in?

A

cell-to-cell interactions, especially during embryonic development

18
Q

When are there abnormal surface markers?

A

cancer cell growth

19
Q

What are desmosomes?

A

Adhering junctions that anchor cells together, especially in tissues subject to stretching. (e.g. skin, heart, uterus)

20
Q

What are tight junctions?

A

Join the lateral edges of epithelial cells near their lumenal (apical) membranes. (tight or leaky)

21
Q

What are gap junctions?

A

‘Communicating’ junctions that allow the movement of charge carrying ions and small molecules between two adjacent cells