Glucose Control Flashcards

1
Q

What is the value for hypoglycaemia?

A

<2.5

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2
Q

What does the brain use as its energy source?

A

glucose

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3
Q

Which hormones influence glucose in the absorptive/post absorptive state?

A

insulin and glucagon

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4
Q

Which hormone regulates glucose in emergencies?

A

Adrenaline

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5
Q

Which hormones regulate glucose glucose during starvation?

A

cortisol and growth hormone

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6
Q

What cells release glucagon?

A

alpha

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7
Q

What cells release insulin?

A

beta

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8
Q

What happens to glucose, insulin and glucagon in the absorptive states?

A

insulin and glucose rise, glucagon falls

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9
Q

What Stimulates conversion of glucose into glycogen?

A

insulin

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10
Q

What stimulates conversion of glycogen into glucose and triglycerides into fatty acids?

A

glucagon

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11
Q

How does insulin promote glucose uptake into muscle and fat?

A

Insulin causes glucose transporter proteins (GLUT4) to be inserted into the plasma membrane of muscle and fat cells from intracellular stores

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12
Q

What inhibits insulin release?

A

sympathetic activity (e.g. exercise) and fall in glucose levels

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13
Q

How are insulin levels detected?

A

Oral glucose tolerance test

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14
Q

In type 1 diabetes, what is the defect in?

A

Defect in beta-cell function

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15
Q

In type 2 diabetes, what is the defect in?

A

Insulin sensitivity

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16
Q

What inhibits glucagon release?

A

Raised blood glucose

Insulin

17
Q

How does glucagon raise glucose?

A

Increasing liver glycogenolysis.
Inhibiting liver glycogen synthesis.
Promoting liver gluconeogenesis.
also promotes lipolysis in liver and adipose tissue.

18
Q

What kind of rhythm does cortisol excretion exhibit?

A

diurnal