membranes Flashcards

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1
Q

3 types of diffusion

A

simple diffusion(no membrane or barrier), diffusion across membrane, facilitated diffusion

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2
Q

What can affect rate of diffusion and why

A

temperature - increased ke particles

number of channel proteins -more sites for diffusion to occur

concentration gradient - larger difference in concentration gradient=faster rate

surface area of membrane = more area to diffusion to occur.

membrane thickness

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3
Q

What is facilitated diffusion

A

Use Channel/carrier proteins to move larger polar substances across the membrane as polar molecules can’t diffuse across hydrophobic interior of membrane

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4
Q

With what type of difusion do we describe the membrane as partially permeable

A

diffusion across membranes

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5
Q

With what type of diffusion do we describe the membrane as selectively permeable

A

facilitated diffusion as the channel/ carrier proteins are specific to individual ions/molecules

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6
Q

What is simple diffusion

A

The net movement of particles from down the concentration gradient- from a high concentration to a low concentration

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7
Q

What happens when concentration equilibrium is reached in diffusion

A

The rate at which the forward and backward reaction occurs is the same (still happens- just hard to tell as occur at the same rate)

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8
Q

With what type of diffusion do we describe the membrane as partially permeable

A

difusion across membrane

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9
Q

What can and cannot difuse across a membrane

A

non polar molecules, partially polar molecules (h20)can diffuse but at low rates
polar molecules cannot pass through as ther charge repels hydrophobic interior

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10
Q

why is rate of difusion faster over short distances than long distances

A

particles move at high speeds
they are constantly colliding which slows overall movement
short distances= less collisions
long distance= increased collisions

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11
Q

What source of energy does diffusion rely on?

A

Energy from the natural random movement of particles

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12
Q

what is active transport

A

movement of molecules or ions from region of low concentration to a region of high concentration

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13
Q

why does active transport require atp

A

active process

requires atp as particles are moving against the concentration gradient

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14
Q

what proteins are used during active transport

A

carrier proteins

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15
Q

outline steps of active transport

A
  • molecule binds on to carrier protein receptors on outside of cell
  • ATP binds on the the carrier protein from the inside of the cell and is hydrolysed to from ADP+Pi
  • The Pi attached to the carrier protein causes the carrier protein to change shape, moving the molecule into the cell
  • As the Pi is released it reacts with an ADP to from ATP
  • carrier protein reverts back to original shape
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16
Q

What is the use of bulk transport and what are the different types

A

bulk transport is used to transport large molecules(enzymes, cells, hormones) through membrane as they are too large to fit through carrier + channel proteins.

  • Endocytosis; phagocytosis, pinocytosis
  • Exocytosis
17
Q

outline process of endocytosis

A
  • cell membrane folds inwards to take in material that needs to be transported within the cell
  • membrane enfold and fuses with the material to form a vesicle
  • vesicle pinches off and travels into the cytoplasm to transfer material where they’re needed
18
Q

outline process of exocytosis

A
  • vesicles formed by the Golgi body move and fuse with the cell membrane
  • contents of the vesicle then released outside the cell
19
Q

what are the uses of atp in active transport

A
  • move particles against concentration gradient
  • movement of vesicles along cytoskeleton
  • changing shape of cells to engulf materials
  • fusion of membranes as vesicles form or meet the cell surface membrane
20
Q

name structures in the cell membrane

A

phospholipid bilayer - hydrophilic phosphate group and hydrophobic core(fatty acids tail)
intrinsic proteins- (channel protein, carrier proteins, glycoproteins),Extrinsic proteins, glycolipids, cholesterol

21
Q

Describe overall structure of intrinsic proteins

A

amino acids with hydrophobic R group that interacts with the hydrophobic core of membrane- keeping it in place

22
Q

Describe the overall structure of extrinsic proteins

A

amino acids with hydrophilic r group attached interacting with polar head of phospholipids

23
Q

function of cholesterol in plasma membrane

A

regulate fluidity of membrane

hydrophobic ends interact with tails of membrane and hydrophilic ends react with phosphate heads , pulling them together

24
Q

difference between channel and carrier proteins

A

channel proteins - provide an alternative pathway for polar molecules and ions to pass through.
carrier - “carries” larger molecules through- specific to certain molecules - involves shape of protein changing

25
Q

role of glycolipids

A

act as cell markers (antigens) to ensure immune system recognises it as a cell that belongs to the body.

26
Q

role of glycoproteins

A

used in cell signalling. Chemicals/hormones bind to receptors on the carbohydrate chain