Membraneous nephropathy Flashcards

1
Q

Types of membraneous nephropathy

A

primary
secondary
alloimmune

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2
Q

Alloimmune membraneous nephropathy

A

neonatal
de novo post kidney transplant
GVHD after HSCT
After enzyme replacement therapies

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3
Q

IgG subclass in primary MN

A

IgG4

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4
Q

Antigen in Primary MN

A

PLA2R

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5
Q

Childhood MN is due to antibodies against

A

bovine serum albumin

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6
Q

Antigen in alloimmune MN

A

Neutral endopeptidase

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7
Q

Rat model for MN

A

Heyman nephritis

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8
Q

Rx for recurrent MN

A

Rituximab

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9
Q

Risk of VTE in MN is high with a serum albumin levels of

A
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10
Q

Regimen used in MN Rx

A

Ponticelli regimen

alternating Cytosan and prednisone for 6 months

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11
Q

Most common cause of nephrotic syndrome in elderly

A

MN

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12
Q

Pointers to a diagnosis of lupus in MN

A

Subendothelial deposits

tubuloreticular inclusions

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13
Q

Biopsy features suggestive of secondary membraneous nephropathy

A

mesangial deposits

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