Membrane transport mechanisms Flashcards
Define Osmosis
movement of solvent from a region of high concentration to a region of low concentration across a semi permeable membrane.
What is osmotic pressure?
water moving from a region of high concentration to a region of low concentration creates a higher pressure in one region. The increase in pressure is osmotic pressure
Osmotic pressure formula
pi=g.C.R.T
mechanisms used by substances to cross membranes
they can be
Energy independent
Energy dependent
Energy independent mechanisms
types of transport: diffusion, facilitated diffusion, osmosis
require channels which can be
non gated: aquaporins & ions channels
gated: ligand gated & voltage gated
Energy dependent
Type of transport: active which can be
primary- requires ATPases directly
secondary-requires multiporters (symporters & antiporters)
Factors affecting rate of diffusion
diffusion depends on kinetic energy, its rate is affected by:
concentration differences across the membrane
membrane electric potential
pressure difference
Factors that increase permeability
oil/water partition coefficient
size of solute
membrane thickness
Equation for measuring diffusion
J= PA(C1-C2) J=flow P=permeability A=area C1 & C2=concentrations in compartments
Differences between diffusion & facilitated diffusion
Diffusion only transport that is not carrier mediated
Facilitated diffusion requires uniporter carriers proteins that are gated (voltage & ligand gated) non gated( aquaporins, potassium & sodium channels)
diffusion and facilitated diffusion will have the same rate but different carrier transporter.
Define diffusion
Random motion of particles
Movement of particles from a region of high concentration to a region of low concentration