Membrane Transport, Epithelial Tissues, and Connective Tissues (LECTURE #2) Flashcards
- maintains internal conditions of the cell
- communicates with the other cells
- described by the fluid mosaic model
The Plasma Membrane
The Plasma Membrane is divided into 5 groups:
1. Phospholipids
#2. Cholesterol
#3. Proteins
#4. Glycolipids
#5. Glycoproteins
- describes how the cell membrane is fluid, flexible, and made of many different components or macromolecules
- allows for the membrane to move with the cell and perform various functions, including maintaining homeostasis, facilitating cellular movement, communication, etc
Fluid Mosaic Model
__(1)__ = not solid
__(2)__ = many different types of macromolecules, embedded and attached
(1) = Fluid
(2) = Mosaic
forms a lipid bilayer in the plasma membrane
Phospholipids
maintains fluidity within the plasma membrane
Cholesterol
a group within the plasma membrane that is subdivided into 2 groups
Proteins
There are 2 types of proteins:
__(1)__ = extends through the lipid bilayer
__(2)__ = attaches to the surface
(1) = Integral Proteins
(2) = Peripheral Proteins
- lipids with a carbohydrate attached by a glycosidic (covalent) bond
- maintain the stability of the cell membrane and facilitate cellular recognition (which is very important in regards to immune response and in the connections that allow cells to connect to one another to form tissues)
Glycolipids
protein with a carbohydrate attached
Glycoprotein
allows some substances to pass through, but not others
Selective Permeability
With Selective Permeability;
- __(1)__ and __(2)__ soluble molecules can pass easily
- __(3)__ pass through moderately easily
- __(4)__ soluble molecules do NOT pass through
(1) = gases
(2) = small, fat
(3) = ions
(4) = large, water
What are the 2 types of transport processes?
1. Passive process
#2. Active process
involve substances moving across the cell membranes WITHOUT energy input
(via D I F F U S I O N)
Passive Transport
passive spread of particles, through random motion, from areas of high to low concentration
Diffusion
What are the 2 types of diffusion?
1. Simple diffusion
#2. Facilitated diffusion
pass without the aid of a membrane protein (unassisted)
Simple Diffusion
requires a carrier protein or channel (assisted)
Facilitated Diffusion
- usually refers to passive processes
- allows ions and molecules to move along their concentrated gradients (facilitated diffusion)
- “open” without changing shape
Channels
- similar to channels, BUT, they have a structural change when they move molecules from one side of the plasma membrane to the other
Carriers
the net movement of water through a selectively permeable membrane from an area of LOW solute concentration TO one of HIGHER solute concentration
Osmosis
Water can pass through the membrane in 2 ways:
__(1)__ = slower
__(2)__ = through an A Q U A P O R I N which is faster
(1) = Simple Diffusion
(2) = Facilitated Diffusion
Which type of diffusion provides a quicker path for water to pass through?
Facilitated Diffusion
protein channels in the plasma membrane allowing the passage of water
Aquaporins
a measure of the solution’s ability to change the volume of cells by altering their water content
Tonicity
Tonicity is broken down into 3 groups:
__(1)__ solution
__(2)__ solution
__(3)__ solution
(1) = Isotonic
(2) = Hypertonic
(3) = Hypotonic
interstitial fluid is the same concentration as cytosol
Isotonic Solution
interstitial fluid is less concentrated than cytosol
Hypotonic Solution
_______ = when the cell bursts
Lysis - aka - Hemolysis
interstitial fluid is more concentrated than cytosol
Hypertonic Solution
_______ = when the cell shrinks
Crenation
moves substances AGAINST their concentration gradient
Active Transport
Active Transport is a process that can be divided into 2 groups…
1, Primary
#2. Secondary
uses ATP (from mitochondria) for energy
Primary active trasnport
does NOT use ATP (uses another energy source)
Secondary active transport
Active Transport Process:
__(1)__ pump is found in all cells, which transports 3 __(2)__ OUT, and 2 __(3)__ INTO the cell. As a result, cells have __(4)__ [Na+], and __(5)__ [K+] inside the cell.
(1) = Na+/K+ Pump
(2) = Na+
(3) = K+
(4) = low
(5) = high
There are 2 Secondary Active Transport Mechanisms. What are they?
Antiporters and Symporters
carry 2 substances across the membrane in OPPOSITE directions
Antiporters
carry 2 substances across the membrane in the SAME direction
Symporters
connect adjacent cells mechanically
Intercellular Junctions
found where a leakproof seal is needed between cells (ex. bladder, stomach)
Tight Junctions
pores (connexons) that allow small substances (like ions) to pass between cells
Gap Junctions