Membrane Transport Flashcards
Water lean body mass %
65.8%
Hydrophilic
Hydrophobic
Amphiphilic
dissolve in water
insoluble in water
mixed properties
Fick’s law of diffusion
Amount moved = Coefficient x Area x Conc gradient
Osmosis
Movement of water or other solvent through a semipermeable membrane that permits the passage of water but not the solute particles.
Osmotic pressure
pressure sufficient to stop the flow of water
Osmotic pressure (pi) = MRT
M - molarity
R - universal gas constant
T - Absolute temperature (310K)
Osmolarity
Osmolality
Moles of solute particles per litre of solution
Moles of solute particles per kg pf water
Osmole - unit of osmotic concentration
Tonicity
The influence of its osmotic concentration on the volume of cells.
Same osmotic conc = iso osmotic.
Not all iso osmotic solutions are isotonic with cells. As the solutions may go down chemical gradient. UREA
Total body water
Extracellular = intracellular water
extracellular = plamsa = intersticial water
Tritiated water for total body water
evans dye for plasma
Plasma membrane size
About 5/6 nanometres
Ion channels
Central pore through which ions diffuse
Passive diffusion
Are selective for ion
High capacity for transport
can be Leak channels or Gated channels
Carrier proteins
Transport small ions finish notes
Transport of macromolecules
Exocytosis - vesicle fuses with plasma membrane and releases components
constituative - performed by all cells to release stuff
regulated - triggered by chemical or electrical signal.
Endocytosis -
Phagocytosis
Pinocytosis
Receptor mediated transport.