Circulation Flashcards
Parts of circulatory system
Cardiovascular - closed - blood
Lymphatic system - open - collects fluid from lymph nodes
Arteries, arterioles, microcirculation and venules/veins
Arteries - transport blood
Arterioles - last arteries with muscular walls
Physical determinants
Ohm’s law
I = V/R
Current = flow of blood
Voltage = pressure difference
R = resistance to flow
Darcy’s law of flow = Q = ^P/R
Blood flow
Laminar flow - smaller vessels
Turbulent flow - large vessels
Speed of flow
v = Q/A
velocity = flow/cross sectional area
Viscosity of blood
Hematocrit ratio
Erythrocyte volume/whole blood volume
Sum of determinants of blood flow
Poiseuille’s law
Q = k ^P r4/nL
k - constant
L- length
^P - pressure difference
r - radius
n - viscoxity
Total peripheral resitance
Q = ^P/R
Vessel radius / diameter
Resistance is reversely proportional to r4.
So r is super important to flow.
Microcirculation
Net filtration = hydrostatic pressure - oncotic pressure.
filtrated fluid = reabsorbed fluid + lymph
High hydrostatic pressure or low oncotic pressure = edema.
3 main parameters of cvs
tissue blood flow
cardiac output
arterial blod pressure