Membrane Transport Flashcards
Types of Transport Mechanism
Passive
Active
Bulk
Passive Transport can be divided into two sub groups which are?
Simple/Passive Diffusion and Facilitated Diffusion
Simply movement from high to low concentration, no transport proteins involved
Simple Diffusion
Leads to diffusion based on concentration and charge
Electrochemical gradient
- Passive transport of a substance across a membrane aided by transport proteins
- Low resistance and does not require energy (e.g., ATP)
Facilitated Diffusion
- transports molecules against their concentration gradient
- Requires energy (e.g. ATP or electrochemical energy)
Active Transport
Transport of macromolecules and large particles through plasma membrane and usually involves vesicle transport/trafficking
Bulk transport
T/F, A protein can be a combination of both passive and active transport
True
Vesicle formation where in there is dynamin involved, ________ surrounds cargo molecules until vesicle maturation at which point they detach
Clathrin coating
Steps of Vesicle Fusion
Tethering
Docking
Fusion
What happens to snare proteins during vesicle fusion>
Transport Vesicle has a v-snare (vesicle snare) while the target membrane has a t-snare (target snare). These two will bind to each other during docking so that membranes coalesce and fuse.
Other names for the v-snare (vesicle snare) forming SNARE Complex in presynaptic neurons
Synaptobrevin or VAMP (Vesicle associated membrane protein)
What are the t-snares forming SNARE Complex in presynaptic neurons?
1 pair of syntaxin
2 pairs of SNAP-25
Interacts with calcium forming a stronger complex with the snare complex. Usually attached to vesicle.
Synaptotagmin
Vesicle Transport mediated by COP II from ER to Golgi
Anterograde
