Membrane transport Flashcards
Active transport
requiring energy and ATP
Passive transport
no energy required
Concentration
the amount of solute (substance) in a solvent (liquid)
Concentration gradient
more solute in one part of a solvent than another
Diffusion
-a function of the concentration gradient
-molecules mix randomly
-solute spreads through solvent
-eliminates concentration gradient
-solutes move down a concentration gradient
Factors affecting diffusion
- distance
- molecule size
- temperature
- gradient size
- electrical forces
Simple diffusion
- diffuse through plasma membrane
- lipid-soluble compounds (alcohols, fatty acids, and steroids)
- dissolved gases (oxygen and carbon dioxide)
Osmosis
- the diffusion of water across the cell membrane
- water molecules diffuse across the membrane toward the solution with more solutes
Osmotic pressure
- the force of a concentration gradient of water
- equals the force (hydrostatic pressure) needed to block osmosis
- no osmosis
Hypotonic
- swells
- less solutes and loses water through osmosis
Hypertonic
- shrivels
- more solutes and gains water by osmosis
Carrier-meditated transport
*- carrier-mediated transport of ions and organic substrates
- facilitated diffusion
- active transport
* characteristics
- Specificity : one transport protein, one set of substrates
- Saturation limits: rate depends on transport proteins, not substrate
- Regulation: cofactors such as hormones
Facilitated diffusion
- passive
Carrier proteins transport molecules too large to fit through channel proteins (glucose, amino acids): - molecules bind to receptor site on carrier protein
- protein changes shape, molecules pass through
- receptor site is specific to certain molecules
Active transport
- move substrates against concentration gradient
- require energy, such as ATP
- ion pumps move ions (Na+, K+, Ca2+, Mg 2+)
- exchange pump countertransports two ions at the same time
Sodium-potassium exchange pump
- active transport
- carrier mediated
- sodium out, potassium in
- 1 ATP moves 3 Na & 2K