Membrane Transport Flashcards
Which transport SYSTEM need ATP?
Active transport
Emphysema is characterised with destruction of respiratory membrane and what will be the surface area and diffusion of gas?
Surface area decreases
Diffusion of gas decreases
It is a passive transport called simple diffusion
Pulmonary fibrosis leads to what changes in fibrotic membrane and diffusion of gases?
Thickness increases
Diffusion decreases
Diffusion is directly proportional to ?
Solubility , area , concentration gradient.
Inversely proportional to size of gas , thickness of membrane
Unit of osmolarity and osmolality
Osmolarity = mosm/Litre of solvent
Osmolality= mosm/kg of solvent
What is the coupling ratio for Na-K pump
3Na:2K
3Na outside and 2K inside
It is an electrogenic pump since movement of charges are unequal
NaKAtpase pumb activity is increased by which hormone’s?
Thyroid hormone
Insulin
Aldosterone
NaKatpase pump blocker drugs are?
Digitalis
Ouabain
Dopamine cause natriuresis in kidneys
Atp is not directly utilized in which transport system?
Secondary active transport
What are the 2 isoforms of SGLT and where it is located?
SGLT 1 : in intestine (basis of ORS solution for treatment of diarrhoea)
SGLT2 : in PCT of kidneys
What is the common element for both exocytosis and endocytosis type of vesicular transport process? and what protiens ate required for each types?
Calcium
Endocytosis- Clathrin , megalin
Exo - snare protein
Exocytosis of neurotransmitter acetylcholine is done by help of which type of snare protein ? and which toxin degrade it and inhibit acetylcholine leada to flaccid paralysis.
SynaptoBrevin
Botulinum toxin
Which transport process show saturation kinetics and which doesn’t shows?
Facilitated diffusion (carrier protien mediated)
Active transport ( channel protein mediated) shows saturation kinetics then plateau point
Simple diffusion doesn’t show saturation kinetis
