Membrane Structure Flashcards

1
Q

What are the intrinsic proteins?

A

Channel proteins
carrier proteins
glycoproteins

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2
Q

What are examples of extrinsic proteins?

A

Enzymes

Proteins that bind cytoskeleton to membrane

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3
Q

What theory describes the structure of the membrane?

A

Cell membrane theory

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4
Q

What informed the cell membrane theory?

A

Fluid Mosaic model

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5
Q

What was used to show the fluid mosaic model?

A
  1. TEM showing bilayer
  2. Fusion of human mouse cells with fluorescent markets in markers
  3. Study of ion channels
  4. SEN freeze fracture
  5. Changes in temp
  6. Endocytosis and exocytosis
  7. Associaton between proteins and membranes
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6
Q

How are the phospholipids arranged in the bilayer?

A

Hydrophobic fatty acid tails point to centre.

Hydrophilic heads point out.

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7
Q

What are phsophlipids made from?

A

1 phosphate group attached to Glycerol

2 fatty acids

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8
Q

What time does cholesterol have in the membrane?

A

Binds phospholopids together to add stabilty.

Prevents phospholopids forming a regular lattice helping fluidity.

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9
Q

Why is the phospholipid group in the phospholipid soluble?

A

Phospholipid is polar i.e. is charged

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10
Q

Why are the fatty acid tails insoluble?

A

Chains have no charge = are non polar

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11
Q

How do phosphlipids moves relative for act other within the membrane?

A

Diffuse laterally

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12
Q

How thick is a phospholipid bilayer?

A

7-10 nm

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13
Q

How many forms can the bikayer take?

A

3

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14
Q

What are the 3 forms the bikayer can take?

A
  1. Micelle - sphere
  2. Bilayer
  3. Liposome - Dohnut
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15
Q

What are the effects of cholesterol at different temperatures?

A

Low temps
Prevent crystallization
High temps
Prevents excessive fluidity

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