Membrane Structure Flashcards
Function of membrane
Selective permeable barrier
Allows control over enclosed chemical environment
Communication
Recognition (receptors of signalling molecules, self antigens, adhesion proteins for structure)
Signal generation from stimuli
Membrane composition
Varies with source Dry weight: 40% lipid 60% protein Small carbohydrate 20% water when hydrated
What type of lipids make up membrane
Amphipathic - contain hydrophilic and hydrophobic groups
Phospholipids
Main lipid of membrane
Polar Head group (choline, amine, AA, sugar)
Fatty acid chains (varied length usually C16-18)
Cis double bond between carbon = kink
Other phospholipid in membrane
Sphingomyelin - a sphingolipid
(No glycerol backbone)
Glycolipid
Types of glycolipids
Contain sugar
Cerebrosides - head group = sugar monomer
Gangliosides - head group = oligosaccharide (many)
Lipid structures
Micelle - circular
Bilayer - sheet, stabilised by water hydrophobic tails inner, hydrophilic heads outside
Phospholipid structure
Choline, phosphate head (hydrophilic)
Glycerol back bone
Fatty acid chain (hydrophobic)
Phospholipid head group examples
Choline
Serine
Inositol
Ethanolamine