Membrane potential Flashcards

1
Q

Do all cells have a membrane potential?

A

Yes

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2
Q

What causes a membrane potential

A

The ions being unevenly distributed outside and inside the cell which creates a potential difference

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3
Q

There is a high concentration of —– and —– oustide the cell (extracellular)

A

Na+ and Cl- oustide the cell

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4
Q

There is a high concentration of —– and —– inside the cell (intracellular)

A

K+ and anions inside the cell (intracellular)

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5
Q

The high concentration of Na and Cl outside the cell and high concentration of K and anions inside the cell creates what

A

It creates an electrochemical gradient across the plasma membrane.

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6
Q

what is a resting membrane potential

A

It is the membrane potential of a cell when its inactive.

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7
Q

What causes a change in membrane potential

A

When the cells becomes more permeable to particular ions so the ions are able to move across a membrane.

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8
Q

Each ion has its own equilibrium potential. what is an equilibrium potential.

A

Its the point where there would be no net movement of an ion across a membrane.

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9
Q

what is the equilibrium potential of Sodium

A

+60mV

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10
Q

what is the equilibrium potential of potassium

A

-80mV

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11
Q

what is the equilibrium potential of a neuron

A
  • 70mV
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12
Q

What do ion channels do

A

They facilitate diffusion

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13
Q

What are ion channels made up of

A

several protein subunits which cross the cell membrane

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14
Q

Why are ion channels highly selective for ions to pass through them

A

because of their pore size (how wide open they are) and the properties of the amino acids that form the pore.

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15
Q

Name the two ways ion channels can be opened.

A

Ligand gated ion channel and Voltage gated ion channel

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16
Q

Explain mechanism of ligand gated ion channel

A
  • ligands gated ion channel have binding sites on them where the ligand (neurotransmitter or drug) attaches to, causing the ion channel to open
17
Q

Explain mechanism of voltage gated ion channel

A

These are sensitive to the membrane potential of the cell, for example voltage gated channel will remain shut during the cell resting potential (the cell resting potential is (-70mV), but when the membrane potential rises (-55 mV) the voltage gated ions will open.