Membrane and Action Potentials Flashcards

0
Q

Saltatory conduction is characteristic of which part of a typical neuron?

A

Axon

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1
Q

_____ Diameter and ___________ cells will transmit an action potential the fastest.

A

Large diameter, Myelinated.

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2
Q

A selectivity filter with carbonyl oxygens is associated with what type of ion channels?

A

Potassium

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4
Q

The resting potential for typical neuron, such as a motor neuron, is best represented by what potential

A

-90 mV

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5
Q

The axolemma is characterized by the presence of what?

A

voltage-gated ion channels and the ability to conduct an action potential.

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6
Q

A neuron is characterized by a single ______ that is variable in length.

A

axon

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7
Q

The _____ is an extension of the cell body and is typically opposite the side of the ________ where the dentrites are located.

A

axon, cell body.

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8
Q

The axon is an extension of the cell body and is covered by the ____________

A

axolemma (plasma membrane)

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9
Q

Diffusion potential:

A

Is caused by an ion concentration difference on either side of a membrane

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10
Q

Nernst Potential

A

is the diffusion potential level across a membrane that exactly opposes the net diffusion of a particular ion through the membrane.

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11
Q

Nernst Equation

A

EMF=z(61.5) x Log ([ion]outside/[ion]inside), z= valence of ion

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12
Q

Voltage gated sodium channels have _____ domains and are arranged in a ________ configuration.

A

four, cylindrical

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13
Q

Define Absolute refractory period:

A

Period during which a second action potential cannot be elicited even with a strong stimulus. Energy is derived directly from breakdown of ATP

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14
Q

Define Relative refractory period:

A

Stronger than normal stimulus can cause action potential.

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15
Q

What are factors that affect propagation speed?

A

Mylination and fiber diameter.

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16
Q

Why do action potentials typically travel in the orthodromic direction?

A

b/c the signal starts at the axon hillock and the refractory period after depolarization takes a while to reset.

17
Q

What are the steps in the generation of an action potential on a neuron axon membrane?

A

Resting stage -90 mV,
depolarization stage: membrane is permeable to sodium. Replolarization stage: K+ channels open more than normal and Na+ close within a few 10,000ths of a second,
Sodium and Potassium conductance.