Meiosis + Sexual Life Cycles Flashcards
Gamete
sex cell, 23
Somatic cell
Body cell
How many chromosomes
46
Autosomes
22 pairs of chromosomes (don’t include sex)
Meiosis I overall function
Diploid to haploid
Interphase (M I)
chromosomes replicated
Prophase I
- Synapsis (homologous chromosomes pair up)
- Crossing over @ chiasmata
Tetrad
4 sister chromatids
Metaphase I
Tetrads line up
Anaphase I
- Pairs of homologus chromosomes separate
-Sister chromatids still attached by centromere
Telophase I & Cytokinesis
- 2 daughter cells produced (genetically different)
- Haploid set of chromosomes in each cell
Meiosis II overall function
create gametes
Prophase II
- no crossing over
- no interphase
- spindle forms
Metaphase II
Chromosomes line up
Telophase II & Cytokinesis
- 4 haploid cells (genetically different)
- Nuclei reappear
Sources of genetic variation
- Crossing over
- Independent assortment of chromosomes
- Random fertilization
Spermatogenesis
Sperm production
Oogenesis
Ova production, creates 1 ovum + 3 polar bodies
Chromosomal mutations
Deletion, duplication, inversion, translocation
Nondisjunction
Failure of homologous chromosomes or sister chromatids to separate, results in abnormal distribution of chromosomes
Types of nondisjunction
Aneuploidy = incorrect # of chromosomes
Polyploidy = 2+ complete sets of chromosomes (3n or 4n)
HeLa Cells
- Cervical cancer cells from Henrietta Lacks
- “Immortal cells” (don’t die after a few divisions)
Anaphase II
Sister chromatids separate