Meiosis and mitosis summerary Flashcards
Name the two divisions of meiosis
meiosis I and meiosis II
Define meiosis
nuclear division which leads to generation of haploid cells
What is a bivalent?
structure formed by two closely aligned duplicated homlogos
What are the 5 stages of prophase I ?
Leptotene Zygotene Pachytene Diplotene Diakinesis
What happens during Leptotene?
homologous chromosomes condense (however, not fully), pair and genetic recombination begins
What happens during Zygotene?
SC (Synaptonemal complex) starts to assemble; synapsis and recombination are taking place
What happens during Pachytene ?
SC is complete, recombination finishes, homologues are very tightly linked
What happens Diplotene?
– disassembly of SC, condensation and shortening of chromosomes After this chiasmata are visible. Homologues can segregate.
Describe the Synaptonemal Complex shape
Each homolog is organized around a protein axial core, and synaptonemal complex forms when these homolog axes are linked by rodshaped transverse filaments. The axial core of each homolog also interacts with the cohesin complexes that hold the sister chromatids together
When does SC assembly begin?
Where does disassembly work?
Assembly begins in early zygotene and completed in pachytene
Disassembled in diplotene
How does meiosis differ from mitosis?
Meiosis I differs from mitosis in 3 major ways: (1) glued together sister kinetochores remain attached to the same spindle pole, (2) chiasmata keep homologs together which allows bi-orientation, (3) centromeric cohesin on sister chromatids remains bound through anaphase I.