Meiosis and mitosis summerary Flashcards

1
Q

Name the two divisions of meiosis

A

meiosis I and meiosis II

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2
Q

Define meiosis

A

nuclear division which leads to generation of haploid cells

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3
Q

What is a bivalent?

A

structure formed by two closely aligned duplicated homlogos

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4
Q

What are the 5 stages of prophase I ?

A
Leptotene
Zygotene
Pachytene
Diplotene 
Diakinesis
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5
Q

What happens during Leptotene?

A

homologous chromosomes condense (however, not fully), pair and genetic recombination begins

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6
Q

What happens during Zygotene?

A

SC (Synaptonemal complex) starts to assemble; synapsis and recombination are taking place

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7
Q

What happens during Pachytene ?

A

SC is complete, recombination finishes, homologues are very tightly linked

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8
Q

What happens Diplotene?

A

– disassembly of SC, condensation and shortening of chromosomes After this chiasmata are visible. Homologues can segregate.

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9
Q

Describe the Synaptonemal Complex shape

A

Each homolog is organized around a protein axial core, and synaptonemal complex forms when these homolog axes are linked by rodshaped transverse filaments. The axial core of each homolog also interacts with the cohesin complexes that hold the sister chromatids together

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10
Q

When does SC assembly begin?

Where does disassembly work?

A

Assembly begins in early zygotene and completed in pachytene

Disassembled in diplotene

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11
Q

How does meiosis differ from mitosis?

A

Meiosis I differs from mitosis in 3 major ways: (1) glued together sister kinetochores remain attached to the same spindle pole, (2) chiasmata keep homologs together which allows bi-orientation, (3) centromeric cohesin on sister chromatids remains bound through anaphase I.

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