Meiosis Flashcards

1
Q

Amount of DNA at each division in meiosis

A

Meiosis I reduces 4c to 2c

meiosis reduces 2c to 1c

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2
Q

describe the 5 stages of prophase I

A

Leptotene (Greek meaning - narrow threads; referring to chromosomes condensing to form string of beads; separate sister chromatids not yet visible)

zygotene (synapsis of homologous chromosomes ; pair is called a bivalent)

pachytene (chromatid pairs begin to separate; crossing over occurs)

diplotene (homologous chromosomes fully separate into 2 pairs of chromatids held only by chiasma)

diakinesis (terminalisation of chiasma, nucleoli/nuclear envelope disappear, centrioles begin to make spindle; chromosomes fully condensed - all 4 chromatids visible )

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3
Q

Metaphase 1

A

bivalents align across the cell equator

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4
Q

Anaphase 1

A

Chromosomes pairs separate and chromosomes move to opp ends of cell

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5
Q

Telophase I

A

Each daughter cell has 2n chromosomes

nuclear envelope may reassemble before or prophase II

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6
Q

Meiosis II

A

Centromeres split at the kinetochores

sister chromatids pulled to opp poles

tetras of haploid cells formed

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7
Q

At which stages of meiosis is genetic variation introduced?

A

Pachytene of prophase I (when crossing over occurs )

anaphase I : independent assortment (random mixtures of maternal and paternal chromosomes at each pole)

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8
Q

Define aneuploidy

A

Abnormal number of chromosomes

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9
Q

Define monosomy

A

When a chromosome is missing from a pair

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10
Q

what happens during leptotene?

A

replicated chromosomes become to condense to become thin threads

the two sister chromatids are to close to distinguish apart

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11
Q

what happens during zygotene?

A

synapsis(alignments) of homologous maternal/paternal chromosome to form bivalents

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12
Q

what happens during pachytene?

A

the pairs of chromosomes become condensed and coiled.

crossing over occurs

chromosomes split into sister chromatids

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13
Q

what happens during diplotene?

A

hoologous chromosomes begin to migrate apart

chromosomes only held together by chiasmata

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14
Q

what happens during diakinesis ?

A

chromosomes fully condensed now ; chiasmata and bivalents fully visible

nucleolus/nuclear envelope disappears

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