Meiosis Flashcards
Amount of DNA at each division in meiosis
Meiosis I reduces 4c to 2c
meiosis reduces 2c to 1c
describe the 5 stages of prophase I
Leptotene (Greek meaning - narrow threads; referring to chromosomes condensing to form string of beads; separate sister chromatids not yet visible)
zygotene (synapsis of homologous chromosomes ; pair is called a bivalent)
pachytene (chromatid pairs begin to separate; crossing over occurs)
diplotene (homologous chromosomes fully separate into 2 pairs of chromatids held only by chiasma)
diakinesis (terminalisation of chiasma, nucleoli/nuclear envelope disappear, centrioles begin to make spindle; chromosomes fully condensed - all 4 chromatids visible )
Metaphase 1
bivalents align across the cell equator
Anaphase 1
Chromosomes pairs separate and chromosomes move to opp ends of cell
Telophase I
Each daughter cell has 2n chromosomes
nuclear envelope may reassemble before or prophase II
Meiosis II
Centromeres split at the kinetochores
sister chromatids pulled to opp poles
tetras of haploid cells formed
At which stages of meiosis is genetic variation introduced?
Pachytene of prophase I (when crossing over occurs )
anaphase I : independent assortment (random mixtures of maternal and paternal chromosomes at each pole)
Define aneuploidy
Abnormal number of chromosomes
Define monosomy
When a chromosome is missing from a pair
what happens during leptotene?
replicated chromosomes become to condense to become thin threads
the two sister chromatids are to close to distinguish apart
what happens during zygotene?
synapsis(alignments) of homologous maternal/paternal chromosome to form bivalents
what happens during pachytene?
the pairs of chromosomes become condensed and coiled.
crossing over occurs
chromosomes split into sister chromatids
what happens during diplotene?
hoologous chromosomes begin to migrate apart
chromosomes only held together by chiasmata
what happens during diakinesis ?
chromosomes fully condensed now ; chiasmata and bivalents fully visible
nucleolus/nuclear envelope disappears