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Anemias Of Decrease Erythropoiesis > Megaloblastic > Flashcards

Megaloblastic Flashcards

1
Q

What causes megaloblastic anemia?

A

Deficiency of folate and B12( cobalamin)

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2
Q

What is defective in this anemia?

A

DNA synthesis is impaired so all cells are affected giving pancytopenia

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3
Q

What is seen in morphology?

A

1) megaloblasts
2) hypersegmented neutrophils FIRST SIGN
3) hyper cellular bone marrow

egg shaped macro-ovalocytes

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Anemias Of Decrease Erythropoiesis (3 decks)

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