Meds exam 2 Flashcards
Lithium
(Category, intended actions)
Drug Category: Mood stabilizers
What other frequently prescribed medications are in this category? Carbamazepine, risperidone
Intended Action (s): resolve symptoms of mania (hyperactivity, pressured speech, poor judgment), decreased incident of mood swings, etc.
Lithium
(SE & AE)
Common Side Effects: fatigue, HA, impaired memory, EKG changes, hypothyroidism, abdominal pain, N/V, leukocytosis, muscle weakness, tremors, polydypsia, polyuria
Adverse Side Effects: seizures, serotonin syndrome
Lithium
(nursing implications, teaching priorities)
Patient Teaching Priorities: changes in sodium will alter the elimination of lithium. Increased sodium intake will increase the renal excretion of lithium.
Nursing Implications: very narrow therapeutic range (0.6-1.2), monitor levels closely and teach patient they will need to get blood work periodically. Look for lithium toxicity (vomiting, diarrhea, slurred speech, lightheadedness, decreased coordination, drowsiness, muscle weakness, tremors, seizures). Stop drug administration if toxicity. Worried also about potassium levels with the salt intake. Not having enough sodium can lead to increased reuptake of lithium→ toxicity. Prelithium workup → cardiac and renal status. Adequate sodium and fluid intake. Teach pt to wear sunscreen
Depakote
(Category, intended actions)
Drug Category: Valproate, anticonvulsant
What other frequently prescribed medications are in this category: carbamazepine, Lamotrigine, Phenytoin
Intended Action(s): increase levels of GABA, → decrease manic episodes
Depakote
SE/AE
Common Side Effects: agitation, dizziness, HA, insomnia, sedation, abdominal pain, diarrhea, N/V, tremors, thrombocytopenia
Adverse Side Effects: suicidal thoughts, hepatotoxicity, pancreatitis, hypothermia, hyperammonemia, agranulocytosis, aplastic anemia
Depakote
nurse impl, pt ed
Patient Teaching Priorities: abrupt withdrawal of drug may lead to seizures
Nursing Implication: assess for suicidal tendencies, restrict amount of drug available to pt. Looks for s/s of DRESS (drug reaction with eosinophilia and systemic symptoms) (fever, rash, lymphadenopathy, myocarditis, etc.) monitor hepatic function and serum ammonia levels. Discontinue therapy if hyperammonemia occurs.
Valproic acid/tegratol
category, action
Drug Category: Anticonvulsant, mood stabilizer
What other frequently prescribed medications are in this category? (Gabapentin), Valproic acid, (Phenytoin)
Intended Action (s): prevention of seizures, relief of neuralgia pain, decreased mania and depressive symptoms.
Valproic acid/tegratol
SE/AE
Common Side Effects: Suicidal thoughts ataxia, drowsiness fatigue. Hepatotoxicity, pancreatitis. Agranulocytosis, anemia, thrombocytopenia.
Adverse Side Effects: blood cell abnormalities, could result in bone marrow depression
Valproic acid/tegratol
nurse imp, pt ed
Patient Teaching Priorities: take doses around the clock as directed and take missed doses ASAP but not right before the next dose. Discontinue gradually to prevent seizures. Avoid grapefruit and grapefruit juice during therapy. Report changes in skin, behavior, rash, sore throat, suicidal thoughts, etc.
Nursing Implications: for bipolar: assess mental status and cognitive abilities before and during therapy. Monitor labs for the first 2 months.
Lamotrigine (Lamictal)
class, use
Anticonvulsent, esp in peds, used in BPD and Mania
Lamotrigine/Lamictal
SE, AE, caution
Significant AE: Stevens Johnson syndrome, hold and call provider if rash
Common SE
weight changes
sedation
upset stomach
Caution in hepatic and renal impairment
SSRIs
drugs, uses
Example drug: Zoloft
generic and trade: Sertraline
What other frequently prescribed medications are in this category? Include 2-3 examples: Fluoxetine (Prozac), Citalopam (Celexa), Escitalopam (lexapro), Fluvoxamine (Luvox)
SSRIs
SE/AE
Common Side Effects: suicide ideation, nausea, insomnia, dry mouth, HA, sexual dysfunction
Adverse Side Effects: serotonin syndrome, Agitation, diaphoresis
SSRIs
nurse imp, pt ed
Patient Teaching Priorities: Take at same time every morning
Nursing Implication: Teach patient that effects may take 4-6 weeks to take effect, report SI
TCAs
meds, uses
Name (generic and trade): clomipramine (anafranil) (first med for OCD)
What other frequently prescribed medications are in this category? Include 2-3 examples: Amitriptyline (Elavil), Imipramine (Trofanil), Noritryptaline (pamelor), Doxepin (sinequan)
Intended Action(s): depression, OCD, migraines, smoking cessation
TCAs
SE/AE
Common Side Effects: drowsiness, dry mouth, sexual problems
Adverse Side Effects: anticholinergic effects, delirium
TCAs
nurse imp, pt ed
Patient Teaching Priorities: TCA’s are sedative so take before bed
Nursing Implications: monitor for suicide ideation and orthostatic hypotension, high suicide effectiveness, high cost
MAOIs
drugs, uses
Example drug: Selegiline
generic and trade: edepryl, emsam
What other frequently prescribed medications are in this category? Include 2-3 examples: phenelzine (nardil), tranylcypromine (parnate), isocarboxazid (Marplan), Moclobemide (Manerix, RIMA)
Intended Action(s): depression, panic, social anxiety
MAOIs
SE/AE
Common Side Effects: runny nose, itching, skin rash
Adverse Side Effects: hypertensive crisis
MAOIs
nurse imp, pt ed
Patient Teaching Priorities: warn patients about signs of hypertensive crisis (headache, shortness of breath, headache, changes in vision), avoid eating tyramine (aged cheese, avocados, chinese food)
Nursing Implication: Monitor blood pressure
Serotonin syndrome
s/s
Confusion, muscle rigidity, diaphoresis, increased HR, fluctuating BP
Serotonin syndrome
nursing imp
vitals, reorient, when was the last med? hold all meds, talk to provider about what you see