Meds Flashcards
Multiple Myeloma
dexamethasone plus thalidomide or lanalidomide -> autologous stem cell transplant
Multiple Myeloma >75yo, not a stem cell transplant candidate
melphan plus prednisone
or bortezomib
CML
imatinib, desatinib, nilotinib (to eradicate the philadelphia chromosome) for life
hydroxyurea can be palliative
Thrombocytosis
don’t have to treat if asymptomatic
hydroxyurea, anagrelide, interferon alpha plus low dose asprin
MDS patients with 5q syndrome
lenalidomide
CLL in younger patients
treat stage III/IV
fludarabine plus cyclophosphamide and rituximab
CLL in older patients
ibrutinib (used to be chlorambucil)
Hairy Cell Lymphoma
cladribine
AML
cytarabine and anthracycline
ATRA for APML (give before Dx confirmed w FISH)
gemtuzumab ozagamicin for older, CD33+ patients
Paroxysmal Nocturnal Hemoglobinuria
if symptomatic: eculizumab
Aplastic Anemia
stem cell transplant if
Hemolytic Anemia
folic acid supplements for everyone!
Cervical Ca Stage II-IV
XRT and cisplatin
Ovarian Ca
surgery plus platinum and paclitaxel
Hormone refractory prostate Ca
docetaxel
Testicular Ca
cisplatin
Colon Ca
FOLFOX (5-FU, leukovorin, oxaliplatin), can add bevacizumab
Pancreatic Ca
5-FU (w XRT), gemcitabine
RCC
sunatinib, sorafenib, paxopanib, temsirolimus, high dose IL2
Hodgkin’s lymphoma
adriamycin, bleomycin, vinblastine, dacarbazine
Follicular lymphoma
rituximab +/- chemo
DLBCL
R-CHOP = rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone
APML
ATRA (w presumptive Dx, don’t wait for FISH)
Burkitt lymphoma
R-hyper-CVAD: rituximab, rapidly cycled cyclophosphamide, vincristine, doxorubicin, dexamethasone
High grade poorly differentiated neuroendocrine tumor
Platinum based chemo
GIST w high risk for recurrence
imatinib
Squamous and non-squamous non small cell lung cancer failing platinum-based chemo
nivolumab (PD-1 inhibitor)
Stage I, II, or III anal SCC
radiation plus chemo (mitomycin and 5-FU)
Prostate Ca bone mets
radium-223
