medorg

Question 1

1,3,7 - Trimethylxanthines

Answer 1

caffeine

Question 2

1,3 - Dimethylxanthines

Answer 2

theophylline

Question 3

3,7 - Dimethylxanthines

Answer 3

Theobromine

Question 4

pramines

Answer 4

Dibenzazepine

Question 6

NSRI with chlorine at c3

Answer 6

clomipramine

Question 6

prototype of NSRI

Answer 6

imipramine

Question 6

only SNRI in dibenzazepine “pramine”

Answer 6

desipramine

Question 7

increases affinity to net and sert

Answer 7

c3-x

Question 8

triptyline

Answer 8

dibenzocycloheptadiene

Question 9

npad

Answer 9

nortriptyline, protriptyline, amitriptyline, doxepine

Question 10

nsri have oxygen at c11

Answer 10

doxepine

Question 11

snri agent kay dibenzocycloheptadiene

Answer 11

np

Question 12

nsri kay dibenzocycloheptadiene

Answer 12

amitriptyline AND doxepine

Question 13

e-isomer selectively inhibits net, and s-isomer inhibits sert

Answer 13

doxepine

Question 14

have propylene moiety

Answer 14

nortriptyline and amitriptyline

Question 15

non tca that uses r- enantiomer is more active

Answer 15

atomoxetine

Question 16

only snri that na dicyclic

Answer 16

atomoxetine

Question 17

inhibits sert and have high affinity and activity for SERT

Answer 17

ssri (selective serotonin reuptake inhibitor)

Question 18

ssri that has more active s-isomer

Answer 18

escitaloprami

Question 19

r isomer of escitalopram

Answer 19

citalopram

Question 20

fluoxetine r isomer is____: s-isomer is____

Answer 20

r isomer is MORE POTENT : s-isomer is HIGHER AFFINITY TO SERT

Question 21

1s, 4r isomer is more active for sert inhibition

Answer 21

sertraline

Question 22

3s,4r isomer more active for sert inhibition

Answer 22

paroxetine

Question 23

e isomer more active for sert inhibition

Answer 23

fluvoxamine

Question 24

used for deamination of amine

Answer 24

mao (monoamine oxidase)

Question 25

substrate of MAO-A

Answer 25

5-HT (serotonin)

Question 26

substrate of MAO-B

Answer 26

NE, DA

Question 27

pmst

Answer 27

phenelzine, moclobemide, selegiline, tranylcypromine

Question 28

reversible inhibitor of mao-a, w/o hypertensive crisis

Answer 28

moclobemide

Question 29

non selective irreversible

Answer 29

phenelzine

Question 30

irreversible inhibitor of mao-b

Answer 30

selegiline

Question 31

5-HT1A and SERT inhibitor

Answer 31

vortioxetine

Question 32

partial serotonin agonist

Answer 32

vilazodone

Question 33

VVAT

Answer 33

vortioxetine, vilazodone, Aripiprazole, Trazodone

Question 34

lipophilic drug PRECURSOR

Answer 34

levadopa

Question 35

COMT inhibitors

Answer 35

entaCAPONE, tolCAPONE

Question 36

DA Agonist and reuptake inhibitor

Answer 36

amantadine

Question 37

da agonist

Answer 37

bromocriptine

Question 38

anticholinergics (tremor management)

Answer 38

benztropine, biperiden,

Question 39

mao-b inhibitors w/o hypertensive crisis

Answer 39

seleGILINE, raGILINE