Mediteranean spotted fever (rickettsioses)

Question 1

Mediterranean spotted fever (agent)

Answer 1

R. conorri

Question 2

Mediterranean spotted fever (vector)

Answer 2

brown dog tick - Rhipicephalus sanguineus

Question 3

Mediterranean spotted fever (time)

Answer 3

june - september

Question 4

Mediterranean spotted fever (place)

Answer 4

sub-saharan africa, europe

Question 5

Mediterranean spotted fever (clinical)

Answer 5

Incubation 10-14 days
High fever, rash and inoculation eschar (black eschar/tache noire) at bite site
Regional lymphadenopathy

Question 6

Mediterranean spotted fever (diagnosis)

Answer 6

Serology - IFA titers 1:64
Cell-culture
PCR - skin biopsy

Question 7

Mediterranean spotted fever (treatment)

Answer 7

Doxycylcine 100mg (2x) for 7-14 days
Chloramphenicol 500mh 1x 7-10 days
Pregnancy - erythromycin