Medicines of Tomorrow Flashcards

Final prep

1
Q

Examples of good bacteria?

A

E. Coli
Lactobacillus

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2
Q

Difference between gram-positive and gram-negative?

A

Gram-positive have no outer lipid membrane and a thick peptidoglycan layer. Stain purple
Gram-negative have an outer membrane and a thinner peptidoglycan layer. Stain red

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3
Q

Three reasons bacteria are essential to us?

A

Protect us from pathogens on skin
Help alert immune response
Break down food in digestive system

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4
Q

What is the Therapeutic index?

A

A measurement on the relative safety of a drug. A ratio between the therapeutic effect and toxic dose

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5
Q

What is the Kirby-Bauer disk diffusion test?

A

A susceptibility test to measure the sensitivity of bacteria to an antibiotic by determining the zone of inhibition on a growth media

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6
Q

Why would you add an acidic compound to do a liquid-liquid extraction?

A

To protonate a base, making it move into the aqueous layer

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7
Q

Why would you add a basic compound to a liquid-liquid extraction?

A

To deprotonate an acid and make it move into the aqueous layer

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8
Q

1-octanol, polar or non-polar?

CH3-CH2-CH2-CH2-CH2-CH2-CH2-CH2-OH

A

Non-polar

Polar end not large enough to counteract non-polar end

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9
Q

Chemical shift value 3 - 5?

A

Halogens

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10
Q

Chemical shift value 7?

A

Aromatics

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11
Q

Chemical shift value 9 - 12?

A

Carboxyl or Aldehydes

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