Medicine- heme/ onc Flashcards

1
Q

clues to HHT

A

plt decrease by >50%
necrotic lesion at injeciton site
arterial/venous clot

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2
Q

gold standard dx for HHT?

A

serotonin release assay

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3
Q

tx of HHT

A

STOP HEP

START direct throbmin inhibitor (argibatran)

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4
Q

FAT RN mnemonic for TTP

A
fever
anemia (MAHA)
thrombocytopenia
Renal 
Neuro
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5
Q

Multiple Myeloma CRAB

A
M= monoclonal spikes of IgG, A (not M)
C= hyperCa
R= renal involvement
A= anemia
B= bone lesions, back pain
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6
Q

mechanism of FVleiden

A

cannot bind activated protein C

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7
Q

what complication do pernicious anemia patients need to be screened for?

A

gastric cancer

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8
Q

treatment of ITP

A

IVIg or glucocorticoids –> observe if only skin manifestations or platelets >30k

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9
Q

coombs in hereditary spherocytosis?

A

NEGATIVE

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10
Q

“dimorphic RBCs” on smear

A

sideroblastic anemia

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11
Q

waldenstrom macroglobulinemia

A

monoclonal M spikes

hypervistcosity sx- diplopia, tinitus, head ache, neuropathy

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