Medicine Flashcards
haemophilia: APTT, PT, Bleeding time changes?
what factor is deficient in A/B types?
APTT increased
PT, bleeding time normal
A: factor 8 deficient
B: factor 9 deficient
von Willebrand disease: APTT, PT, bleeding time changes?
APTT, bleeding time increased, PT normal
Vit K deficiency: APTT, PT, bleeding time changes?
APTT, PT increased
bleeding time normal
A 68-year-old male presents to his GP having noticed enlarge lymph nodes in neck, axillae and groin. Blood tests show low Hb, high wcc. What is most likely dx?
CLL
olanzapine common SE
increase appetite, weight gain, DM, lipid changes, sedation
findings on fundoscopy in papilloedema?
venous engorgement loss of venous pulsation blurring of optic disc margin elevation of optic disc loss of optic cup Paton's lines
SE of sulphonylureas
hypoglycaemia
weight gain
hypontraemia
beware in preg
SE of pioglitazone
avoid if HF, fluid retention, bladder ca
weight gain
hypoglycaemia
what type of med is liraglutide, exanetide?
SE?
indication to use?
GLP1 mimetic
weight loss, reduce appetite, reduce CVS events
N&V, pancreatitis
use if tripe therapy, still >58mmol/L + BMI>35
what type of med is linagliptin, sitagliptin?
SE?
DPP4 inhib
good if need weight loss
GI discomfort
what type of med is dapagliflozin?
SE?
SGLT2 inhib
UTI, thrush, euglycaemia ketoacidosis
weight loss, reduce cardiac mortality
ECG changes - hypokalaemia
A prolonged PR interval, depressed ST segment, flattened T waves and prominent U waves.
ECG changes - hypocalcaemia
prlonged QT
double duct sign = ? dx?
ca of head of pancreas
caused by dilation of the common bile duct and pancreatic duct in response to the tumou
Obesity with abnormal LFTs - ?
NAFLD
