MEDICATIONS MOA

Question 1

What antibiotic inhibits 30S ribosomal subunit?

Answer 1

Aminoglycosides - i.e. Gentamicin
Tetracyclines

Question 1

What antibiotic inhibits 50S ribosomal subunit?

Answer 1

Macrolides
Clindamycin
Linezolid
Streptogramins
Chloramphenicol

Question 2

What antibiotic inhibits cell wall synthesis?

Answer 2

Penicillins
Cephalosporins
Carbapenems
Monobactams

Question 3

What antibiotic inhibits topoisomerase?

Answer 3

Fluoroquinolones - i.e. Ciprofloxacin

Question 4

What antibiotic inhibits RNA polymerase?

Answer 4

Rifampin

Question 5

What antibiotic inhibits DNA gyrase

Answer 5

Quinolones

Question 6

What antibiotic inhibits folate synthesis?

Answer 6

Sulfonamides
Trimethoprim

Question 7

MOA - binding to antithrombin III and converted to rapid inactivator of coagulation factors

Answer 7

Heparin

Question 8

MOA - inhibits the synthesis of vitamin K dependent clotting factors

Answer 8

Coumadin

Question 9

Active direct thrombin inhibitor that inhibits clot-bound and circulating thrombin

Answer 9

Dabigatran

Question 10

Orally available direct factor Xa inhibitor

Answer 10

Rivaroxaban

Question 11

Dopamine agonists

Answer 11

Cabergoline
Bromocriptine

Question 12

Mechanism of action of azole medications

Answer 12

Reduce cell membrane ergosterol synthesis > increases fungal cell membrane permeability > cell lysis

Question 13

Nucleotide analog that competitively inhibits HBV polymerase

Answer 13

Tenofovir