Medications Flashcards
Chlorpromazine
Typical (traditional) anti-psychotic
Thioridazine
Typical (traditional) anti-psychotic
Haloperidol
Typical (traditional) anti-psychotic (tablet, liquid, or depot)
Trifluoperazine
Typical (traditional) anti-psychotic
Thiothixene
Typical (traditional) anti-psychotic
Zuclopenthixol
Typical (traditional) anti-psychotic
Flupentixol decanoate
Typical (traditional) anti-psychotic
Fluphenazine decanoate
Typical (traditional) anti-psychotic
Fluanxol
Depot typical (traditional) anti-psychotic
Olanzapine
Atypical (newer) anti-psychotic. Significant weight gain, diabetes and lipid abnormalities risks.
Risperidone
Atypical (newer) anti-psychotic. Also available in depot.
Quetiapine
Atypical (newer) anti-psychotic with low EPS risk. Often used as sedating agent or anxiolytic.
Ziprasidone
Atypical (newer) anti-psychotic with low diabetes risk. Must be taken with fat-containing meal/snack.
Aripiprazole
“Third generation” anti-psychotic: unique complex action, dopamine system stabilizer.
Clozapine (use and regime)
Gold standard atypical, last resort antipsychotic, for treatment resistant schizophrenia. Standard: 300-600mg/day, any more can cause epilepsy, max. is 900mg/day. “Clozapine workup” before commencing treatment. If 2 days are missed during treatment, doses have to be retitrated. Bloods weekly for 18 weeks, then monthly. WBC and ANC (absolute neutrophil count) monitored due to agranulocytosis risk.
Agranulocytosis
Decreased neutrophil WBCs - develops suddenly, characterised by sore throat, fever, malaise and leukopenia. High risk of cold/flu.
Sulpiride
Typical (traditional) anti-psychotic
Paliperidone
Depot atypical (newer) anti-psychotic
Clozapine side effects
Constipation, sedation, hypersalivation, acid reflux, urinary incontinence, postural hypotension, myocarditis (arrhythmia, ECG abnormalities), tachycardia, paralytic ileus (obstruction in ileum), epilepsy (high doses), agranulocytosis.
Anticholinergics
Given oral or IM. Treats EPS. Causes dry mouth, constipation, blurred vision. E.g. Benztropine, procylidine
Benztropine
Anticholinergic
Procylidine
Anticholinergic
Diazepam
Benzodiazepine, anxiolytic. Also used for alcohol withdrawals.
Clonazepam
Benzodiazepine anxiolytic
Alprazolam
Benzodiazepine anxiolytic
Lorazepam
Benzodiazepine, anxiolytic
Temazepam
Benzodiazepine anxiolytic
Zopiclone
Sedative/sleeping pill (anxiolytic)