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H - pediatrics > Medications > Flashcards

Medications Flashcards

1
Q

Cyproheptadine

A

Serotonin receptor antagonist, used in serotonin syndrome

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2
Q

Bromocriptine

A

Dopamine agonist - used in neuroleptic malignant syndrome

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3
Q

Propylthiouracil

A

Hyperthyroidism
Inhibits conversion of T4 to T3 in extrathyroidal tissue
Advantageous in neonatal thyrotoxicosis
Dosed TID

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4
Q

Methimazole

A

Hyperthyroidism
10x more potent than Propylthiouracil
Inhibit incorporation of trapped inorganic iodide into organic compounds
Clinical response 3-6 weeks, control 3-4 months
Remission 25% by 2 years
If relapse will happen usually within 3 months, always by 6 months
Earlier remission: >13 years old, boys, inc BMI, small goitres, and modestly elevated T3

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5
Q

Arginine HCl 10%

A

Urea cycle defect treatment

210-600 mg/kg IV

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6
Q

Biotin

A

Treatment for organic acidemia

10 mg IV or PO

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7
Q

Carnitine

A

Treatment for fatty acid defects or organic acidemia

50-400 mg/kg IV or PO

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8
Q

Pyroxidine

A

Vit B6
Treatment of Pyroxidine-dependent sz
Intractable seizures in the neonatal period

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9
Q

Sodium benzoate

A

Treatment of urea Cycle defect
Binds amino acids –> excretion –> decreases ammonia levels
Nitrogen scavenger

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10
Q

Phenylacetate

A

Treatment of urea cycle defects
Nitrogen scavenger
250 mg/kg IV

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11
Q

Thiamine

A

Treatment of MSUD or primary lactic acidosis

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12
Q

Nitisinone

A

Tyrosinemia I treatment
inhibitor of oxidation of parahydroxyphenylpyruvic acid –> eliminates production of toxic succinylacetone (this is not a problem in type II and III)

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13
Q

Phenytoin and fosphenytoin side effects

A

Arrhythmias, bradycardia, hypotension –> continuous bp/ECG monitoring

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14
Q

Phenobarbital side effects

A

Sedation, resp depression, hypotension

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15
Q

Pyridoxine

A

Vit B6

Intractable infant seizures may be caused by an undiagnosed metabolic disorder such as Pyroxidine-dependent epilepsy

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16
Q

Deferoxamine

A

Iron chelation therapy for prevention of hemosiderosis (inevitable and fatal consequence of prolonged transfusion therapy)

17
Q

PGE side effects (5)

A 
apnea
bradycardia 
hypotention
fever
edema
flushing
pyloric stenosis
18
Q

Baby with goiter - what meds was mom on?

A

Ones that contain iodine

CVS: amiodarone

19
Q

Indomethacin complications

A 
NEC
decreased Plt aggregation 
transient oliguria, increased Cr
HypoNa
HyperKa
Hypoglycemia
GI perforation

H - pediatrics (15 decks)

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