Medications

Question 1

Etidronate

Answer 1

Used for Paget Disease
Etidronate, it works like all other bisphosphonates in that it reduces osteoclastic activity.
UNLIKE the other bisphosphonates, it PREVENTS bone calcification.

for this reason etidronate is indicated for short term use only - 2 weeks to 3 months. If long term use is employed you run the risk of osteomalacia

Question 2

Alendronate

Answer 2

Osteoporosis, Not Paget Dx

Question 3

Plicamycin

Answer 3

Paget Dx

RNA synthesis inhibitor

Question 4

Adenosine

Answer 4

Identify +/- Terminate SVT

Question 5

Amiodarone

Answer 5

SVT
VT
Slows impulse generation and/or conduction of SA/AV nodes

Question 6

When is Amiodarone contraindicated?

Answer 6

Bradyarrhythmias

Question 7

IV glucagon

Answer 7

Used to treat CCB and/or Beta-Blocker toxicity

Question 8

S/Sx of Exertional Heat Stroke

Answer 8

- Acute Confusion
Extreme Hyperthermia (> 40.5°C)

Question 9

Malignant Hyperthermia is often induced by which medications?

Answer 9

Halothane

Succinylcholine

Question 10

Fluphenazine

Answer 10

“Typical” Anti-psychotic
Commonly injected Q2-3weeks in patients with POOR compliance

More potent than haloperidol (Inc. side effect profile)

can cause hypothermia by inhibiting the bodies shivering response and/or autonomic thermoregulation

Avoid prolonged cold exposure

Question 11

MC side effects of amytripiline

Answer 11

• WEIGHT GAIN
• dizziness
• insomnia

Question 12

MC side effects of cephalexin

Answer 12

• rash
• vomiting
• diarrhea
• abdominal pain

Question 13

Tolterodine

Answer 13

Urge Incontinence

Overactive Bladder Sx

Question 14

Vaginal Estrogen

Answer 14

• Urinary incontinence with concomitant vaginal atrophy

Question 15

Flecainide, Propafenone

Answer 15

Class IC anti-arrhythmics
Tx: AFib in patients with STRUCTURALLY NORMAL hearts

• slowest rate of drug binding & dissociation from SC
• QRS & QT prolongation are normal occurrences EXCEPT in faster HR given use dependence of the drug.

Question 16

Digoxin

Answer 16

ATP-ase-dependent Na+/K+ pump

• enhances vagal tone
• slows conduction through AV node
• used in older, sick hearts to enhance automaticity and delay after-depolarizations.

Side effects:

• bradyarrhythmias (younger, healthier patients)
• Ventricular ectomy & tachyarrhythmias (older patients with underlying cardiac dx)

Question 17

Use dependence QRS / QT prolongation occurs with which anti-arrhytmic Rx?

Answer 17

1. Class IC&raquo_space;> IB, IA

2. Class IV

Question 18

MC side effects of TMP-SMX

Answer 18

• Rash
• Neutropenia
• Hyperkalemia
• Elevated Transaminases

Question 19

Need to treat PCP PNA but patient is sulfa allergic - what do you use?

What do you need to take into consideration when looking at these other drug regimens?

Answer 19

(A) IV Pentamidine
(B) PO Atovaquone
(C) Trimethoprim + Dapsone
(D) IV/PO Clindamycin + PO Primaquine

Dapsone: Hemolytic Anemia in G6PD Df.
Primaquine: Methemoglobinemia, Hemolytic Anemia in G6PD Df.